Disorders of the enteric nervous system—a holistic view

B Niesler, S Kuerten, IE Demir… - … reviews Gastroenterology & …, 2021 - nature.com
The enteric nervous system (ENS) is the largest division of the peripheral nervous system
and closely resembles components and functions of the central nervous system. Although …

Enteric nervous system development: A crest cell's journey from neural tube to colon

N Nagy, AM Goldstein - Seminars in cell & developmental biology, 2017 - Elsevier
The enteric nervous system (ENS) is comprised of a network of neurons and glial cells that
are responsible for coordinating many aspects of gastrointestinal (GI) function. These cells …

Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

MJ Workman, MM Mahe, S Trisno, HM Poling… - Nature medicine, 2017 - nature.com
The enteric nervous system (ENS) of the gastrointestinal tract controls many diverse
functions, including motility and epithelial permeability. Perturbations in ENS development …

The neural crest

R Mayor, E Theveneau - Development, 2013 - journals.biologists.com
The neural crest (NC) is a highly migratory multipotent cell population that forms at the
interface between the neuroepithelium and the prospective epidermis of a develo** …

Biology of GDNF and its receptors—relevance for disorders of the central nervous system

CF Ibáñez, JO Andressoo - Neurobiology of disease, 2017 - Elsevier
A targeted effort to identify novel neurotrophic factors for midbrain dopaminergic neurons
resulted in the isolation of GDNF (glial cell line-derived neurotrophic factor) from the …

The developmental etiology and pathogenesis of Hirschsprung disease

NEB Tjaden, PA Trainor - Translational research, 2013 - Elsevier
The enteric nervous system is the part of the autonomic nervous system that directly controls
the gastrointestinal tract. Derived from a multipotent, migratory cell population called the …

A gene regulatory network orchestrates neural crest formation

T Sauka-Spengler, M Bronner-Fraser - Nature reviews Molecular cell …, 2008 - nature.com
The neural crest is a multipotent, migratory cell population that is unique to vertebrate
embryos and gives rise to many derivatives, ranging from the peripheral nervous system to …

Vitamin D3 and brain development

D Eyles, J Brown, A Mackay-Sim, J McGrath, F Feron - Neuroscience, 2003 - Elsevier
Evidence for the presence of the vitamin D receptor in brain implies this vitamin may have
some function in this organ. This study investigates whether vitamin D3 acts during brain …

Enteric nervous system development: migration, differentiation, and disease

JI Lake, RO Heuckeroth - American Journal of Physiology …, 2013 - journals.physiology.org
The enteric nervous system (ENS) provides the intrinsic innervation of the bowel and is the
most neurochemically diverse branch of the peripheral nervous system, consisting of two …

Neural crest cell plasticity and its limits

NM Le Douarin, S Creuzet, G Couly, E Dupin - 2004 - journals.biologists.com
The neural crest (NC) yields pluripotent cells endowed with migratory properties. They give
rise to neurons, glia, melanocytes and endocrine cells, and to diversemesenchymal' …