Despite having been identified as the organism that causes tuberculosis in 1882,
Mycobacterium tuberculosis has managed to still evade our understanding of the protective …

Tuberculosis is the leading infectious disease killer globally due to a single pathogen.
Despite wide deployment of standard drug regimens, modern diagnostics and a vaccine …

Mycobacterium tuberculosis (Mtb) is the leading cause of death from infection worldwide.
The only available vaccine, BCG (Bacillus Calmette–Guérin), is given intradermally and has …

Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is the most common cause of
death in people living with human immunodeficiency virus (HIV). Intra-dermal Bacille …

A mucosal route of vaccination could prevent severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) replication at the site of infection and limit transmission. We …

Tuberculosis (TB) remains a major health threat. Although a vaccine has been available for
almost 100 years termed Bacille Calmette-Guérin (BCG), it is insufficient and better vaccines …

Abstract Development of new vaccines tailored for difficult-to-target diseases is hampered by
a lack of diverse adjuvants for human use, and none of the currently available adjuvants …

In addition to antibiotics, vaccination is considered among the most efficacious methods in
the control and the potential eradication of infectious diseases. New safe and effective …

Analysis of multi-modal datasets can identify multi-scale interactions underlying biological
systems but can be beset by spurious connections due to indirect impacts propagating …

In the face of ineffective vaccines, increasing antibiotic resistance and the decline in new
antibacterial drugs in the pipeline, tuberculosis (TB) still remains pandemic. Exposure to …