Ischemia-reperfusion injury reduces long term renal graft survival: mechanism and beyond

H Zhao, A Alam, AP Soo, AJT George, D Ma - EBioMedicine, 2018 - thelancet.com
Ischemia-reperfusion injury (IRI) during renal transplantation often initiates non-specific
inflammatory responses that can result in the loss of kidney graft viability. However, the long …

Marked variation in the definition and diagnosis of delayed graft function: a systematic review

SG Yarlagadda, SG Coca, AX Garg… - Nephrology Dialysis …, 2008 - academic.oup.com
Background. The term delayed graft function (DGF) is commonly used to describe the need
for dialysis after receiving a kidney transplant. DGF increases morbidity after transplantation …

[HTML][HTML] Each additional hour of cold ischemia time significantly increases the risk of graft failure and mortality following renal transplantation

A Debout, Y Foucher, K Trébern-Launay, C Legendre… - Kidney international, 2015 - Elsevier
Although cold ischemia time has been widely studied in renal transplantation area, there is
no consensus on its precise relationship with the transplantation outcomes. To study this, we …

[HTML][HTML] Rates and determinants of progression to graft failure in kidney allograft recipients with de novo donor-specific antibody

C Wiebe, IW Gibson, TD Blydt-Hansen… - American Journal of …, 2015 - Elsevier
Understanding rates and determinants of clinical pathologic progression for recipients with
de novo donor-specific antibody (dnDSA), especially subclinical dnDSA, may identify …

[HTML][HTML] Renal transplantation after ex vivo normothermic perfusion: the first clinical study

ML Nicholson, SA Hosgood - American Journal of Transplantation, 2013 - Elsevier
Ex vivo normothermic perfusion (EVNP) is a novel method of preservation that restores
circulation and allows an organ to regain function prior to transplantation. The aim of this …

Uterus transplantation: a rapidly expanding field

M Brännström, PD Kähler, R Greite, J Mölne… - …, 2018 - journals.lww.com
Uterus Transplantation: A Rapidly Expanding Field : Transplantation Uterus Transplantation:
A Rapidly Expanding Field : Transplantation Log in or Register Subscribe to journalSubscribe …

[HTML][HTML] Foxp3+ regulatory T cells participate in repair of ischemic acute kidney injury

MT Gandolfo, HR Jang, SM Bagnasco, GJ Ko… - Kidney international, 2009 - Elsevier
T lymphocytes modulate early ischemia-reperfusion injury in the kidney; however, their role
during repair is unknown. We studied the role of TCRβ+ CD4+ CD25+ Foxp3+ regulatory T …

[HTML][HTML] Protocol of a randomised controlled, open-label trial of ex vivo normothermic perfusion versus static cold storage in donation after circulatory death renal …

SA Hosgood, K Saeb-Parsy, C Wilson, C Callaghan… - BMJ open, 2017 - bmjopen.bmj.com
Introduction Ex vivo normothermic perfusion (EVNP) is a novel technique that reconditions
the kidney and restores renal function prior to transplantation. Phase I data from a series of …

Cold ischemia is a major determinant of acute rejection and renal graft survival in the modern era of immunosuppression

D Mikhalski, KM Wissing, L Ghisdal, N Broeders… - …, 2008 - journals.lww.com
Background. The aim of our study was to examine, in a recent cohort of kidney transplant
recipients who have received modern immunosuppressive therapy, the respective role of …

[HTML][HTML] Nitric oxide in kidney transplantation

GJ Dugbartey - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Kidney transplantation is the treatment of choice for patients with kidney failure. Compared
to dialysis therapy, it provides better quality of life and confers significant survival advantage …