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Cancer stem cells as key drivers of tumour progression
AZ Ayob, TS Ramasamy - Journal of biomedical science, 2018 - Springer
Abstract Background Cancer stem cells (CSCs) are subpopulations of cancer cells sharing
similar characteristics as normal stem or progenitor cells such as self-renewal ability and …
similar characteristics as normal stem or progenitor cells such as self-renewal ability and …
Systems biology of cancer metastasis
Cancer metastasis is no longer viewed as a linear cascade of events but rather as a series
of concurrent, partially overlap** processes, as successfully metastasizing cells assume …
of concurrent, partially overlap** processes, as successfully metastasizing cells assume …
Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation
SY Lee, EK Jeong, MK Ju, HM Jeon, MY Kim, CH Kim… - Molecular cancer, 2017 - Springer
Radiation therapy is one of the major tools of cancer treatment, and is widely used for a
variety of malignant tumours. Radiotherapy causes DNA damage directly by ionization or …
variety of malignant tumours. Radiotherapy causes DNA damage directly by ionization or …
Cancer stem cells: The root of tumor recurrence and metastases
C Peitzsch, A Tyutyunnykova, K Pantel… - Seminars in cancer …, 2017 - Elsevier
Metastatic tumors are the cause of more than 90% of cancer related deaths. Metastasis
formation can be considered as a culmination of the Darwinian evolutionary process within …
formation can be considered as a culmination of the Darwinian evolutionary process within …
Glucose metabolism on tumor plasticity, diagnosis, and treatment
X Lin, Z **ao, T Chen, SH Liang, H Guo - Frontiers in oncology, 2020 - frontiersin.org
Malignant cells support tumor proliferation and progression by adopting to metabolic
changes. Tumor cells altered metabolism by increasing glucose uptake and fermentation of …
changes. Tumor cells altered metabolism by increasing glucose uptake and fermentation of …
Distinctive properties of metastasis-initiating cells
T Celià-Terrassa, Y Kang - Genes & development, 2016 - genesdev.cshlp.org
Primary tumors are known to constantly shed a large number of cancer cells into systemic
dissemination, yet only a tiny fraction of these cells is capable of forming overt metastases …
dissemination, yet only a tiny fraction of these cells is capable of forming overt metastases …
Cancer stem cell metabolism and potential therapeutic targets
V Snyder, TC Reed-Newman, L Arnold… - Frontiers in …, 2018 - frontiersin.org
Malignant tumors contain heterogeneous populations of cells in various states of
proliferation and differentiation. The presence of cancer stem or initiating cells is a well …
proliferation and differentiation. The presence of cancer stem or initiating cells is a well …
[HTML][HTML] Cancer metabolism in space and time: beyond the Warburg effect
P Danhier, P Bański, VL Payen, D Grasso… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Altered metabolism in cancer cells is pivotal for tumor growth, most notably by providing
energy, reducing equivalents and building blocks while several metabolites exert a …
energy, reducing equivalents and building blocks while several metabolites exert a …
Lipid metabolism alteration contributes to and maintains the properties of cancer stem cells
Lipids, the basic components of the cell membrane, execute fundamental roles in almost all
the cell activities including cell-cell recognition, signalling transduction and energy supplies …
the cell activities including cell-cell recognition, signalling transduction and energy supplies …
A promising new approach to cancer therapy: Targeting iron metabolism in cancer stem cells
M El Hout, L Dos Santos, A Hamaï… - Seminars in Cancer …, 2018 - Elsevier
Iron is an essential nutrient that facilitates cell proliferation and growth. Iron can be
detrimental, however. The ability of iron to cycle between oxidized and reduced forms …
detrimental, however. The ability of iron to cycle between oxidized and reduced forms …