Mesothelin expression in human tumors: a tissue microarray study on 12,679 tumors

S Weidemann, P Gagelmann, N Gorbokon, M Lennartz… - Biomedicines, 2021 - mdpi.com
Mesothelin (MSLN) represents an attractive molecule for targeted cancer therapies. To
identify tumors that might benefit from such therapies, tissue microarrays including 15,050 …

Identification of tetraspanin-7 as a target of autoantibodies in type 1 diabetes

KA McLaughlin, CC Richardson, A Ravishankar… - Diabetes, 2016 - Am Diabetes Assoc
The presence of autoantibodies to multiple-islet autoantigens confers high risk for the
development of type 1 diabetes. Four major autoantigens are established (insulin, glutamate …

The endothelial-enriched lncRNA LINC00607 mediates angiogenic function

F Boos, JA Oo, T Warwick, S Günther… - Basic research in …, 2023 - Springer
Long non-coding RNAs (lncRNAs) can act as regulatory RNAs which, by altering the
expression of target genes, impact on the cellular phenotype and cardiovascular disease …

SCOUP: a probabilistic model based on the Ornstein–Uhlenbeck process to analyze single-cell expression data during differentiation

H Matsumoto, H Kiryu - BMC bioinformatics, 2016 - Springer
Background Single-cell technologies make it possible to quantify the comprehensive states
of individual cells, and have the power to shed light on cellular differentiation in particular …

PIVOT: platform for interactive analysis and visualization of transcriptomics data

Q Zhu, SA Fisher, H Dueck, S Middleton… - BMC …, 2018 - Springer
Background Many R packages have been developed for transcriptome analysis but their
use often requires familiarity with R and integrating results of different packages requires …

miRNome and proteome profiling of human keratinocytes and adipose derived stem cells proposed miRNA-mediated regulations of epidermal growth factor and …

H Shahin, S Abdallah, J Das, W He, I El-Serafi… - International Journal of …, 2023 - mdpi.com
Wound healing is regulated by complex crosstalk between keratinocytes and other cell
types, including stem cells. In this study, a 7-day direct co-culture model of human …

Genome-wide classification of epigenetic activity reveals regions of enriched heritability in immune-related traits

M Stricker, W Zhang, WY Cheng, S Gazal, C Dendrou… - Cell genomics, 2024 - cell.com
Epigenetics underpins the regulation of genes known to play a key role in the adaptive and
innate immune system (AIIS). We developed a method, EpiNN, that leverages epigenetic …

De novo RNA sequence assembly during in vivo inflammatory stress reveals hundreds of unannotated lincRNAs in human blood CD14+ monocytes and in adipose …

C Xue, X Zhang, H Zhang, JF Ferguson… - Physiological …, 2017 - journals.physiology.org
Long intergenic noncoding RNAs (lincRNAs) have emerged as key regulators of cellular
functions and physiology. Yet functional lincRNAs often have low, context-specific and tissue …

The endothelial-specific LINC00607 mediates endothelial angiogenic function

F Boos, JA Oo, T Warwick, S Günther, JI Ponce… - bioRxiv, 2022 - biorxiv.org
Long non-coding RNAs (lncRNAs) can act as regulatory RNAs which, by altering the
expression of target genes, impact on the cellular phenotype and cardiovascular disease …

Inhibin alpha expression in human tumors: a tissue microarray study on 12,212 tumors

S Weidemann, NA Noori, M Lennartz, V Reiswich… - Biomedicines, 2022 - mdpi.com
As a result of its expression in corresponding normal cell types, inhibin alpha (INHA) is used
as an immunohistochemical marker for adrenocortical neoplasms and testicular or ovarian …