Mesothelin expression in human tumors: a tissue microarray study on 12,679 tumors
S Weidemann, P Gagelmann, N Gorbokon, M Lennartz… - Biomedicines, 2021 - mdpi.com
Mesothelin (MSLN) represents an attractive molecule for targeted cancer therapies. To
identify tumors that might benefit from such therapies, tissue microarrays including 15,050 …
identify tumors that might benefit from such therapies, tissue microarrays including 15,050 …
Identification of tetraspanin-7 as a target of autoantibodies in type 1 diabetes
KA McLaughlin, CC Richardson, A Ravishankar… - Diabetes, 2016 - Am Diabetes Assoc
The presence of autoantibodies to multiple-islet autoantigens confers high risk for the
development of type 1 diabetes. Four major autoantigens are established (insulin, glutamate …
development of type 1 diabetes. Four major autoantigens are established (insulin, glutamate …
The endothelial-enriched lncRNA LINC00607 mediates angiogenic function
F Boos, JA Oo, T Warwick, S Günther… - Basic research in …, 2023 - Springer
Long non-coding RNAs (lncRNAs) can act as regulatory RNAs which, by altering the
expression of target genes, impact on the cellular phenotype and cardiovascular disease …
expression of target genes, impact on the cellular phenotype and cardiovascular disease …
SCOUP: a probabilistic model based on the Ornstein–Uhlenbeck process to analyze single-cell expression data during differentiation
H Matsumoto, H Kiryu - BMC bioinformatics, 2016 - Springer
Background Single-cell technologies make it possible to quantify the comprehensive states
of individual cells, and have the power to shed light on cellular differentiation in particular …
of individual cells, and have the power to shed light on cellular differentiation in particular …
PIVOT: platform for interactive analysis and visualization of transcriptomics data
Background Many R packages have been developed for transcriptome analysis but their
use often requires familiarity with R and integrating results of different packages requires …
use often requires familiarity with R and integrating results of different packages requires …
miRNome and proteome profiling of human keratinocytes and adipose derived stem cells proposed miRNA-mediated regulations of epidermal growth factor and …
Wound healing is regulated by complex crosstalk between keratinocytes and other cell
types, including stem cells. In this study, a 7-day direct co-culture model of human …
types, including stem cells. In this study, a 7-day direct co-culture model of human …
Genome-wide classification of epigenetic activity reveals regions of enriched heritability in immune-related traits
Epigenetics underpins the regulation of genes known to play a key role in the adaptive and
innate immune system (AIIS). We developed a method, EpiNN, that leverages epigenetic …
innate immune system (AIIS). We developed a method, EpiNN, that leverages epigenetic …
De novo RNA sequence assembly during in vivo inflammatory stress reveals hundreds of unannotated lincRNAs in human blood CD14+ monocytes and in adipose …
Long intergenic noncoding RNAs (lincRNAs) have emerged as key regulators of cellular
functions and physiology. Yet functional lincRNAs often have low, context-specific and tissue …
functions and physiology. Yet functional lincRNAs often have low, context-specific and tissue …
The endothelial-specific LINC00607 mediates endothelial angiogenic function
F Boos, JA Oo, T Warwick, S Günther, JI Ponce… - bioRxiv, 2022 - biorxiv.org
Long non-coding RNAs (lncRNAs) can act as regulatory RNAs which, by altering the
expression of target genes, impact on the cellular phenotype and cardiovascular disease …
expression of target genes, impact on the cellular phenotype and cardiovascular disease …
Inhibin alpha expression in human tumors: a tissue microarray study on 12,212 tumors
S Weidemann, NA Noori, M Lennartz, V Reiswich… - Biomedicines, 2022 - mdpi.com
As a result of its expression in corresponding normal cell types, inhibin alpha (INHA) is used
as an immunohistochemical marker for adrenocortical neoplasms and testicular or ovarian …
as an immunohistochemical marker for adrenocortical neoplasms and testicular or ovarian …