State-dependent effects of neural stimulation on brain function and cognition
Invasive and non-invasive brain stimulation methods are widely used in neuroscience to
establish causal relationships between distinct brain regions and the sensory, cognitive and …
establish causal relationships between distinct brain regions and the sensory, cognitive and …
Applications of focused ultrasound in the brain: from thermoablation to drug delivery
Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of …
clinic represents the culmination of decades of research. Lying at the convergence of …
Centering cognitive neuroscience on task demands and generalization
Cognitive neuroscience seeks generalizable theories explaining the relationship between
behavioral, physiological and mental states. In pursuit of such theories, we propose a …
behavioral, physiological and mental states. In pursuit of such theories, we propose a …
The prefrontal cortex, pathological anxiety, and anxiety disorders
Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …
Non-invasive transcranial ultrasound stimulation for neuromodulation
Transcranial ultrasound stimulation (TUS) holds great potential as a tool to alter neural
circuits non-invasively in both animals and humans. In contrast to established non-invasive …
circuits non-invasively in both animals and humans. In contrast to established non-invasive …
Ultrasound technologies for imaging and modulating neural activity
Visualizing and perturbing neural activity on a brain-wide scale in model animals and
humans is a major goal of neuroscience technology development. Established electrical and …
humans is a major goal of neuroscience technology development. Established electrical and …
Transcranial focused ultrasound-mediated neurochemical and functional connectivity changes in deep cortical regions in humans
Low-intensity transcranial ultrasound stimulation (TUS) is an emerging non-invasive
technique for focally modulating human brain function. The mechanisms and neurochemical …
technique for focally modulating human brain function. The mechanisms and neurochemical …
Focused ultrasound excites cortical neurons via mechanosensitive calcium accumulation and ion channel amplification
Ultrasonic neuromodulation has the unique potential to provide non-invasive control of
neural activity in deep brain regions with high spatial precision and without chemical or …
neural activity in deep brain regions with high spatial precision and without chemical or …
Intrinsic functional neuron-type selectivity of transcranial focused ultrasound neuromodulation
Transcranial focused ultrasound (tFUS) is a promising neuromodulation technique, but its
mechanisms remain unclear. We hypothesize that if tFUS parameters exhibit distinct …
mechanisms remain unclear. We hypothesize that if tFUS parameters exhibit distinct …
Ultrasound as a versatile tool for short-and long-term improvement and monitoring of brain function
Treating the brain with focused ultrasound (FUS) at low intensities elicits diverse responses
in neurons, astroglia, and the extracellular matrix. In combination with intravenously injected …
in neurons, astroglia, and the extracellular matrix. In combination with intravenously injected …