Centrosomes are microtubule-organizing centres of animal cells. They influence the
morphology of the microtubule cytoskeleton, function as the base for the primary cilium and …

Many human tumours show centrosome aberrations, indicating an underlying deregulation
of centrosome structure, duplication or segregation. Centrosomes organize microtubule …

Centrioles and centrosomes have an important role in animal cell organization, but it is
uncertain to what extent they are essential for animal development. The Drosophila protein …

Cytotoxic T lymphocytes (CTLs) destroy virally infected and tumorigenic cells by releasing
the contents of specialized secretory lysosomes—termed 'lytic granules'—at the …

Centrosomes, which were first described in the late 19th century, are found in most animal
cells and undergo duplication once every cell cycle so that their number remains stable, like …

Centrosomes of animal cells and spindle pole bodies of fungi are the major microtubule
nucleating centers. Recent studies indicate that their capacity to organize microtubule arrays …

Cell division is commonly thought to involve the equal distribution of cellular components
into the two daughter cells. During many cell divisions, however, proteins, membrane …

Cytokinesis is the process by which cells physically separate after the duplication and
spatial segregation of the genetic material. A number of general principles apply to this …

Microtubules are highly dynamic cellular polymers made of αβ-tubulin and associated
proteins. They play a key role during mitosis, participating in the exact organization and …

▪ Abstract Completion of the cell cycle requires the temporal and spatial coordination of
chromosome segregation with mitotic spindle disassembly and cytokinesis. In budding …