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Identification of RNA structures and their roles in RNA functions
The development of high-throughput RNA structure profiling methods in the past decade has
greatly facilitated our ability to map and characterize different aspects of RNA structures …
greatly facilitated our ability to map and characterize different aspects of RNA structures …
Rock, scissors, paper: How RNA structure informs function
RNA can fold back on itself to adopt a wide range of structures. These range from relatively
simple hairpins to intricate 3D folds and can be accompanied by regulatory interactions with …
simple hairpins to intricate 3D folds and can be accompanied by regulatory interactions with …
In vivo single-molecule analysis reveals COOLAIR RNA structural diversity
Cellular RNAs are heterogeneous with respect to their alternative processing and secondary
structures, but the functional importance of this complexity is still poorly understood. A set of …
structures, but the functional importance of this complexity is still poorly understood. A set of …
MicroRNAs: emerging regulators in horticultural crops
Horticulture is one of the oldest agricultural practices with great popularity throughout the
world. Horticultural crops include fruits, vegetables, ornamental plants, as well as medicinal …
world. Horticultural crops include fruits, vegetables, ornamental plants, as well as medicinal …
An interpretable RNA foundation model for exploring functional RNA motifs in plants
The complex 'language'of plant RNA encodes a vast array of biological regulatory elements
that orchestrate crucial aspects of plant growth, development and adaptation to …
that orchestrate crucial aspects of plant growth, development and adaptation to …
The plant noncoding transcriptome: a versatile environmental sensor
Plant noncoding RNA transcripts have gained increasing attention in recent years due to
growing evidence that they can regulate developmental plasticity. In this review article, we …
growing evidence that they can regulate developmental plasticity. In this review article, we …
CRISPR/Cas13d targeting suppresses repeat-associated non-AUG translation of C9orf72 hexanucleotide repeat RNA
A hexanucleotide GGGGCC repeat expansion in the non-coding region of the C9orf72 gene
is the most common genetic mutation identified in patients with amyotrophic lateral sclerosis …
is the most common genetic mutation identified in patients with amyotrophic lateral sclerosis …
Small RNAs in plant immunity and virulence of filamentous pathogens
Gene silencing guided by small RNAs governs a broad range of cellular processes in
eukaryotes. Small RNAs are important components of plant immunity because they …
eukaryotes. Small RNAs are important components of plant immunity because they …
Domain organization, expression, subcellular localization, and biological roles of ARGONAUTE proteins in Arabidopsis
ARGONAUTE (AGO) proteins are the final effectors of small RNA-mediated transcriptional
and post-transcriptional silencing pathways. Plant AGO proteins are essential for preserving …
and post-transcriptional silencing pathways. Plant AGO proteins are essential for preserving …
LncRNA CFAR promotes cardiac fibrosis via the miR-449a-5p/LOXL3/mTOR axis
M Zhang, B Zhang, X Wang, J Song, M Tong… - Science China Life …, 2023 - Springer
Cardiac fibrosis is one of the crucial pathological factors in the heart, and various cardiac
conditions associated with excessive fibrosis can eventually lead to heart failure. However …
conditions associated with excessive fibrosis can eventually lead to heart failure. However …