Multidrug resistance of cancer cells and the vital role of P-glycoprotein
P-glycoprotein (P-gp) is a major factor in the multidrug resistance phenotype in cancer cells.
P-gp is a protein that regulates the ATP-dependent efflux of a wide range of anticancer …
P-gp is a protein that regulates the ATP-dependent efflux of a wide range of anticancer …
Multi-Drug Resistance and Breast Cancer Progression via Toll-Like Receptors (TLRs) Signaling
Toll-like receptors (TLRs) are essential receptors involved in inflammation and innate
immunity. Various types of cancer cells, as well as innate immune cells, express TLRs …
immunity. Various types of cancer cells, as well as innate immune cells, express TLRs …
Resveratrol in breast cancer treatment: from cellular effects to molecular mechanisms of action
Breast cancer (BC) is one of the most common cancers in females and is responsible for the
highest cancer-related deaths following lung cancer. The complex tumor microenvironment …
highest cancer-related deaths following lung cancer. The complex tumor microenvironment …
[HTML][HTML] Effective targeting of breast cancer by the inhibition of P-glycoprotein mediated removal of toxic lipid peroxidation byproducts from drug tolerant persister cells
Therapy resistance has long been considered to occur through the selection of pre-existing
clones equipped to survive and quickly regrow, or through the acquisition of mutations …
clones equipped to survive and quickly regrow, or through the acquisition of mutations …