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[HTML][HTML] Formation, function, and pathology of RNP granules
Ribonucleoprotein (RNP) granules are diverse membrane-less organelles that form through
multivalent RNA-RNA, RNA-protein, and protein-protein interactions between RNPs. RNP …
multivalent RNA-RNA, RNA-protein, and protein-protein interactions between RNPs. RNP …
Mammalian stress granules and P bodies at a glance
Stress granules (SGs) and processing bodies (PBs) are membraneless ribonucleoprotein-
based cellular compartments that assemble in response to stress. SGs and PBs form …
based cellular compartments that assemble in response to stress. SGs and PBs form …
Ewing sarcoma
Ewing sarcoma is the second most frequent bone tumour of childhood and adolescence that
can also arise in soft tissue. Ewing sarcoma is a highly aggressive cancer, with a survival of …
can also arise in soft tissue. Ewing sarcoma is a highly aggressive cancer, with a survival of …
A new phase of networking: the molecular composition and regulatory dynamics of mammalian stress granules
SR Millar, JQ Huang, KJ Schreiber, YC Tsai… - Chemical …, 2023 - ACS Publications
Stress granules (SGs) are cytosolic biomolecular condensates that form in response to
cellular stress. Weak, multivalent interactions between their protein and RNA constituents …
cellular stress. Weak, multivalent interactions between their protein and RNA constituents …
It's not just a phase: function and characteristics of RNA-binding proteins in phase separation
HJ Wiedner, J Giudice - Nature structural & molecular biology, 2021 - nature.com
Biomolecular condensates that form via phase separation are increasingly regarded as
coordinators of cellular reactions that regulate a wide variety of biological phenomena …
coordinators of cellular reactions that regulate a wide variety of biological phenomena …
Stress granules and processing bodies in translational control
P Ivanov, N Kedersha… - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
Stress granules (SGs) and processing bodies (PBs) are non-membrane-enclosed RNA
granules that dynamically sequester translationally inactive messenger ribonucleoprotein …
granules that dynamically sequester translationally inactive messenger ribonucleoprotein …
Principles and properties of stress granules
DSW Protter, R Parker - Trends in cell biology, 2016 - cell.com
Stress granules are assemblies of untranslating messenger ribonucleoproteins (mRNPs)
that form from mRNAs stalled in translation initiation. Stress granules form through …
that form from mRNAs stalled in translation initiation. Stress granules form through …
RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome
Stress granules are higher order assemblies of nontranslating mRNAs and proteins that
form when translation initiation is inhibited. Stress granules are thought to form by protein …
form when translation initiation is inhibited. Stress granules are thought to form by protein …
Protein phase separation: a new phase in cell biology
Cellular compartments and organelles organize biological matter. Most well-known
organelles are separated by a membrane boundary from their surrounding milieu. There are …
organelles are separated by a membrane boundary from their surrounding milieu. There are …
A G3BP1-interacting lncRNA promotes ferroptosis and apoptosis in cancer via nuclear sequestration of p53
Long noncoding RNAs (lncRNA) have been associated with various types of cancer;
however, the precise role of many lncRNAs in tumorigenesis remains elusive. Here we …
however, the precise role of many lncRNAs in tumorigenesis remains elusive. Here we …