Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …

Symptoms of neurological diseases emerge through the dysfunction of neural circuits whose
diffuse and intertwined architectures pose serious challenges for delivering therapies. Deep …

Deep brain stimulation (DBS) is an effective treatment for common movement disorders and
has been used to modulate neural activity through delivery of electrical stimulation to key …

Background Closed loop deep brain stimulation (clDBS) in Parkinson's disease (PD) using
subthalamic (STN) neural feedback has been shown to be efficacious only in the acute post …

Abstract See Moll and Engel (doi: 10.1093/aww308) for a scientific commentary on this
article. Brain regions dynamically engage and disengage with one another to execute …

Background Millions of patients around the world are affected by neurological and
psychiatric disorders. Deep brain stimulation (DBS) is a device-based therapy that could …

Continuous high‐frequency DBS is an established treatment for essential tremor and
Parkinson's disease. Current developments focus on trying to widen the therapeutic window …

In patients with Parkinson's disease and in animal models of this disorder, neurons in the
basal ganglia and related regions in thalamus and cortex show changes that can be …

Synchronized oscillations within and between brain areas facilitate normal processing, but
are often amplified in disease. A prominent example is the abnormally sustained beta …