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Endothelial cell dysfunction in cardiac disease: driver or consequence?
JD Allbritton-King, G García-Cardeña - Frontiers in Cell and …, 2023 - frontiersin.org
The vascular endothelium is a multifunctional cellular system which directly influences blood
components and cells within the vessel wall in a given tissue. Importantly, this cellular …
components and cells within the vessel wall in a given tissue. Importantly, this cellular …
[HTML][HTML] VEGF-A in cardiomyocytes and heart diseases
M Braile, S Marcella, L Cristinziano… - International Journal of …, 2020 - mdpi.com
The vascular endothelial growth factor (VEGF), a homodimeric vasoactive glycoprotein, is
the key mediator of angiogenesis. Angiogenesis, the formation of new blood vessels, is …
the key mediator of angiogenesis. Angiogenesis, the formation of new blood vessels, is …
Endothelial cell–cardiomyocyte crosstalk in heart development and disease
The crosstalk between endothelial cells and cardiomyocytes has emerged as a requisite for
normal cardiac development, but also a key pathogenic player during the onset and …
normal cardiac development, but also a key pathogenic player during the onset and …
Fasting, non-fasting and postprandial triglycerides for screening cardiometabolic risk
Fasting triacylglycerols have long been associated with cardiovascular disease (CVD) and
other cardiometabolic conditions. Evidence suggests that non-fasting triglycerides (ie …
other cardiometabolic conditions. Evidence suggests that non-fasting triglycerides (ie …
CD44 promotes angiogenesis in myocardial infarction through regulating plasma exosome uptake and further enhancing FGFR2 signaling transduction
Q Zhang, L Chen, L Huang, H Cheng, L Wang, L Xu… - Molecular …, 2022 - Springer
Background Since angiogenesis occurs as the pathological process following myocardial
infarction to alleviate ischemia, therapeutic angiogenesis has been proposed to be a …
infarction to alleviate ischemia, therapeutic angiogenesis has been proposed to be a …
Panax notoginseng Saponins for Treating Coronary Artery Disease: A Functional and Mechanistic Overview
L Duan, X **ong, J Hu, Y Liu, J Li… - Frontiers in Pharmacology, 2017 - frontiersin.org
Coronary artery disease (CAD) is a major public health problem and the chief cause of
morbidity and mortality worldwide. Panax notoginseng, a valuable herb in traditional …
morbidity and mortality worldwide. Panax notoginseng, a valuable herb in traditional …
Mechanoregulation of vascular endothelial growth factor receptor 2 in angiogenesis
B Miller, MK Sewell-Loftin - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
The endothelial cells that compose the vascular system in the body display a wide range of
mechanotransductive behaviors and responses to biomechanical stimuli, which act in …
mechanotransductive behaviors and responses to biomechanical stimuli, which act in …
[HTML][HTML] Induced dysregulation of ACE2 by SARS-CoV-2 plays a key role in COVID-19 severity
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the cause of COVID-19, is
reported to increase the rate of mortality worldwide. COVID-19 is associated with acute …
reported to increase the rate of mortality worldwide. COVID-19 is associated with acute …
Systems biology of angiogenesis signaling: Computational models and omics
Angiogenesis is a highly regulated multiscale process that involves a plethora of cells, their
cellular signal transduction, activation, proliferation, differentiation, as well as their …
cellular signal transduction, activation, proliferation, differentiation, as well as their …
An injectable hydrogel combining medicine and matrix with anti-inflammatory and pro-angiogenic properties for potential treatment of myocardial infarction
J Feng, M **ng, W Qian, J Qiu… - Regenerative Biomaterials, 2023 - academic.oup.com
One of the main illnesses that put people's health in jeopardy is myocardial infarction (MI).
After MI, damaged or dead cells set off an initial inflammatory response that thins the …
After MI, damaged or dead cells set off an initial inflammatory response that thins the …