Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative option for a variety
of malignant and non-malignant hematological and congenital diseases. Due to the fact that …

Relapse is a major cause of treatment failure after allogeneic hematopoietic stem cell
transplantation (alloHSCT). Treatment options for relapse have been inadequate, and the …

Positive detection of minimal residual disease (MRD) by multichannel flow cytometry (MFC)
prior to hematopoietic cell transplantation (HCT) of patients with acute lymphoblastic …

Purpose Over the past four decades, allogeneic hematopoietic cell transplantation (alloHCT)
has evolved as a curative modality for patients with hematologic diseases. This study …

Abstract Background and Objectives: The wide variability in pharmacokinetics of busulfan in
children is one factor influencing outcomes such as toxicity and event-free survival. A meta …

Busulfan (Bu) is used as a myeloablative agent in conditioning regimens before allogeneic
hematopoietic cell transplantation (allo-HCT). In line with strategies explored in adults …

Abstract Purpose of Review The remarkable improvement in the prognosis of children with
acute lymphoblastic leukemia (ALL) has been mainly achieved through the administration of …

Lower-intensity conditioning regimens for haploidentical blood or marrow transplantation
(BMT) are safe and efficacious for adult patients with hematologic malignancies. We report …

Minimal residual disease (MRD) during early chemotherapy is a powerful predictor of
relapse in acute lymphoblastic leukaemia (ALL) and is used in children to determine …

The safety and efficacy of reduced-intensity conditioning (RIC) regimens for the treatment of
pediatric acute myeloid leukemia is unknown. We compared the outcome of allogeneic …