The “old” and the “new” antibiotics for MDR gram-negative pathogens: for whom, when, and how

I Karaiskos, S Lagou, K Pontikis, V Rapti… - Frontiers in public …, 2019 - frontiersin.org
The recent expansion of multidrug resistant and pan-drug-resistant pathogens poses
significant challenges in the treatment of healthcare associated infections. An important …

[HTML][HTML] Polymyxins and bacterial membranes: a review of antibacterial activity and mechanisms of resistance

C Ayoub Moubareck - Membranes, 2020 - mdpi.com
Following their initial discovery in the 1940s, polymyxin antibiotics fell into disfavor due to
their potential clinical toxicity, especially nephrotoxicity. However, the dry antibiotic …

Ceftazidime-avibactam for the treatment of serious gram-negative infections with limited treatment options: a systematic literature review

A Soriano, Y Carmeli, AS Omrani, LSP Moore… - Infectious diseases and …, 2021 - Springer
Introduction A systematic literature review was undertaken to evaluate real-world use of
ceftazidime-avibactam for infections due to aerobic Gram-negative organisms in adults with …

Study of Antimicrobial Resistance, Biofilm Formation, and Motility of Pseudomonas aeruginosa Derived from Urine Samples

T de Sousa, M Hébraud, O Alves, E Costa, L Maltez… - Microorganisms, 2023 - mdpi.com
Pseudomonas aeruginosa causes urinary tract infections associated with catheters by
forming biofilms on the surface of indwelling catheters. Therefore, controlling the spread of …

Multidrug-resistant Acinetobacter baumannii outbreaks: a global problem in healthcare settings

MNL Kurihara, RO Sales, KE Silva… - Revista da Sociedade …, 2020 - SciELO Brasil
INTRODUCTION: The increase in the prevalence of multidrug-resistant Acinetobacter
baumannii infections in hospital settings has rapidly emerged worldwide as a serious health …

Trends in antibiotic resistance of nosocomial and community-acquired infections in Italy

P Cerini, FR Meduri, F Tomassetti, I Polidori… - Antibiotics, 2023 - mdpi.com
The World Health Organization has recently identified three categories of pathogens,
namely: critical, high, and medium priority, according to the need for new antibiotics. Critical …

Veterinary informatics: forging the future between veterinary medicine, human medicine, and One Health initiatives—a joint paper by the Association for Veterinary …

JL Lustgarten, A Zehnder, W Shipman, E Gancher… - JAMIA …, 2020 - academic.oup.com
Objectives This manuscript reviews the current state of veterinary medical electronic health
records and the ability to aggregate and analyze large datasets from multiple organizations …

Extended and continuous infusion of novel protected β-lactam antibiotics: a narrative review

F Venuti, M Trunfio, AG Martson, F Lipani… - Drugs, 2023 - Springer
Consolidated data from pharmacokinetic and pharmacodynamic studies support the
administration of β-lactam antibiotics in prolonged infusion (ie, extended or continuous) to …

Prevalence of colistin resistance in clinical isolates of Pseudomonas aeruginosa: a systematic review and meta-analysis

N Narimisa, A Keshtkar, L Dadgar-Zankbar… - Frontiers in …, 2024 - frontiersin.org
Objective The emergence of resistance to colistin, the last resort for treating severe
infections caused by Pseudomonas aeruginosa, poses a significant threat to public health …

Acinetobacter baumannii – a neglected pathogen in veterinary and environmental health in Germany

G Wareth, H Neubauer, LD Sprague - Veterinary research communications, 2019 - Springer
The emergence and global spread of drug resistant Acinetobacter (A.) baumannii is a cause
of great concern. The current knowledge on antibiotic resistance in A. baumannii from …