Lomefloxacin-loaded PLGA hollow nanospheres for healing MRSA-infected diabetic wound; optimization, in vitro and in vivo studies

RM Gebreel, MM Abdellatif, A Attia - Journal of Drug Delivery Science and …, 2024 - Elsevier
This study aimed to develop an efficient nano-delivery system to treat MRSA-infected
diabetic wounds by continuously providing Lomefloxacin (Lome) in a constant pattern with …

In vitro and ex vivo evaluation of chitosan gel containing metformin-loaded polymeric nanoparticles for topical treatment of melanoma

Z Eke, D Orgul, G Varan, N Erdoğar - Drug Development and …, 2024 - Taylor & Francis
Objective The purpose of this study was to prepare and evaluate chitosan (CS) gel
containing metformin hydrochloride (MET)-loaded polycaprolactone (PCL) nanoparticles …

Docetaxel and Niclosamide-loaded Nanofiber systems for Improved Chemo-therapeutic Activity and Resistance Reversal in Prostate Cancer

S Shah, P Famta, G Vambhurkar, R Kumar… - Drug Development …, 2025 - Taylor & Francis
Objective–The objective of the study was to tackle the recurrence of PCa post-surgery and to
re-sensitize the DTX-resistant PC-3 cells to chemo-therapy using NIC. Significance …

QbD Manoeuvred Niclosamide Laden Polylactic-co-Glycolic Acid Nanoparticles-Impregnated Gelatin Nanofibers for the Management of Oral Carcinoma

S Shah, P Famta, R Kumar, G Vambhurkar, G Pandey… - BioNanoScience, 2025 - Springer
Oral carcinoma (OC) is the leading cause of mouth deformation and mortality in the world. It
is the 6th most frequent cancer globally. OC is aggressive cancer-forming tumors that invade …

Modulação da Microbiota Intestinal como Estratégia Terapêutica no Tratamento do Melanoma

TC Bernardi, V Mazzardo, I Dallacort… - Brazilian Journal of …, 2024 - bjihs.emnuvens.com.br
A microbiota intestinal, uma comunidade complexa de microrganismos, tem emergido como
modulador crucial na homeostase do hospedeiro e na resposta a doenças como o …