Nanomedicine has been extensively explored to enhance the efficacy of chemotherapy with
modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …

Navigation through the bulk tumour, entry into the blood vasculature, survival in the
circulation, exit at distant sites and resumption of proliferation are all steps necessary for …

Nanotechnology offers several attractive design features that have prompted its exploration
for cancer diagnosis and treatment. Nanosized drugs have a large loading capacity, the …

Intratumoral immunosuppressive microenvironment (ISM) remains the dominant limitation to
disable oncological immunotherapy such as immunogenic cell death (ICD). To resolve the …

Circular RNAs have been identified as naturally occurring RNAs that are highly represented
in the eukaryotic transcriptome. Although a large number of circRNAs have been reported …

Hypoxia as one characteristic hallmark of solid tumors has been demonstrated to be
involved in cancer metastasis and progression, induce severe resistance to oxygen …

Gas-involving cancer theranostics have attracted considerable attention in recent years due
to their high therapeutic efficacy and biosafety. We have reviewed the recent significant …

The widespread development of nanocarriers to deliver chemotherapeutics to specific tumor
sites has been motivated by the lack of selective targeting during chemotherapy inducing …

Although photodynamic therapy (PDT) has served as an important strategy for treatment of
various diseases, it still experiences many challenges, such as shallow penetration of light …

The tumor microenvironment (TME) has profound impacts on cancer progression and
remodeling of the TME has emerged as a strategy to facilitate cancer therapy. Recently …