Optogenetics at the presynapse

BR Rost, J Wietek, O Yizhar, D Schmitz - Nature neuroscience, 2022 - nature.com
Optogenetic actuators enable highly precise spatiotemporal interrogation of biological
processes at levels ranging from the subcellular to cells, circuits and behaving organisms …

Smart photochromic materials triggered with visible light

AL Leistner, ZL Pianowski - European Journal of Organic …, 2022 - Wiley Online Library
Molecular photoswitches reversibly convert the energy of light into a variety of structural
changes at the molecular level. They can be integrated into smart materials with broad …

Optogenetic stimulation probes with single-neuron resolution based on organic LEDs monolithically integrated on CMOS

AJ Taal, I Uguz, S Hillebrandt, CK Moon… - Nature …, 2023 - nature.com
The use of optogenetic stimulation to evoke neuronal activity in targeted neural populations—
enabled by opsins with fast kinetics, high sensitivity and cell-type and subcellular specificity …

Organoid intelligence (OI)–the ultimate functionality of a brain microphysiological system

L Smirnova, IEM Pantoja, T Hartung - ALTEX-Alternatives to animal …, 2023 - altex.org
Understanding brain function remains challenging as work with human and animal models
is complicated by compensatory mechanisms, while in vitro models have been too simple …

Extrinsic neuromodulation in the rodent olfactory bulb

D Brunert, M Rothermel - Cell and Tissue Research, 2021 - Springer
Evolutionarily, olfaction is one of the oldest senses and pivotal for an individual's health and
survival. The olfactory bulb (OB), as the first olfactory relay station in the brain, is known to …

The neural circuit architecture of social hierarchy in rodents and primates

E Ferreira-Fernandes, J Peça - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Social status is recognized as a major determinant of social behavior and health among
animals; however, the neural circuits supporting the formation and navigation of social …

Emerging biophysical techniques for probing synaptic transmission in neurodegenerative disorders

MB Kale, NL Wankhede, AK Bishoyi, S Ballal, R Kalia… - Neuroscience, 2024 - Elsevier
Plethora of research has shed light on the critical role of synaptic dysfunction in various
neurodegenerative disorders (NDDs), including Alzheimer's disease (AD), Parkinson's …

[HTML][HTML] A deep-learning strategy to identify cell types across species from high-density extracellular recordings

M Beau, DJ Herzfeld, F Naveros, ME Hemelt… - bioRxiv, 2024 - ncbi.nlm.nih.gov
High-density probes allow electrophysiological recordings from many neurons
simultaneously across entire brain circuits but don't reveal cell type. Here, we develop a …

Electrophysiological monitoring of neurochemical-based neural signal transmission in a human brain–spinal cord assembloid

J Son, SJ Park, T Ha, SN Lee, HY Cho, JW Choi - ACS sensors, 2022 - ACS Publications
Combining human brain organoids holds great potential in recapitulating the human brain's
histological features and modeling neural disorders. However, current combined-brain …

Connecting circuits with networks in addiction neuroscience: A salience network perspective

AK Cushnie, W Tang, SR Heilbronner - International journal of molecular …, 2023 - mdpi.com
Human neuroimaging has demonstrated the existence of large-scale functional networks in
the cerebral cortex consisting of topographically distant brain regions with functionally …