Optogenetics at the presynapse
Optogenetic actuators enable highly precise spatiotemporal interrogation of biological
processes at levels ranging from the subcellular to cells, circuits and behaving organisms …
processes at levels ranging from the subcellular to cells, circuits and behaving organisms …
Smart photochromic materials triggered with visible light
AL Leistner, ZL Pianowski - European Journal of Organic …, 2022 - Wiley Online Library
Molecular photoswitches reversibly convert the energy of light into a variety of structural
changes at the molecular level. They can be integrated into smart materials with broad …
changes at the molecular level. They can be integrated into smart materials with broad …
Optogenetic stimulation probes with single-neuron resolution based on organic LEDs monolithically integrated on CMOS
The use of optogenetic stimulation to evoke neuronal activity in targeted neural populations—
enabled by opsins with fast kinetics, high sensitivity and cell-type and subcellular specificity …
enabled by opsins with fast kinetics, high sensitivity and cell-type and subcellular specificity …
Organoid intelligence (OI)–the ultimate functionality of a brain microphysiological system
Understanding brain function remains challenging as work with human and animal models
is complicated by compensatory mechanisms, while in vitro models have been too simple …
is complicated by compensatory mechanisms, while in vitro models have been too simple …
Extrinsic neuromodulation in the rodent olfactory bulb
D Brunert, M Rothermel - Cell and Tissue Research, 2021 - Springer
Evolutionarily, olfaction is one of the oldest senses and pivotal for an individual's health and
survival. The olfactory bulb (OB), as the first olfactory relay station in the brain, is known to …
survival. The olfactory bulb (OB), as the first olfactory relay station in the brain, is known to …
The neural circuit architecture of social hierarchy in rodents and primates
E Ferreira-Fernandes, J Peça - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Social status is recognized as a major determinant of social behavior and health among
animals; however, the neural circuits supporting the formation and navigation of social …
animals; however, the neural circuits supporting the formation and navigation of social …
Emerging biophysical techniques for probing synaptic transmission in neurodegenerative disorders
MB Kale, NL Wankhede, AK Bishoyi, S Ballal, R Kalia… - Neuroscience, 2024 - Elsevier
Plethora of research has shed light on the critical role of synaptic dysfunction in various
neurodegenerative disorders (NDDs), including Alzheimer's disease (AD), Parkinson's …
neurodegenerative disorders (NDDs), including Alzheimer's disease (AD), Parkinson's …
[HTML][HTML] A deep-learning strategy to identify cell types across species from high-density extracellular recordings
M Beau, DJ Herzfeld, F Naveros, ME Hemelt… - bioRxiv, 2024 - ncbi.nlm.nih.gov
High-density probes allow electrophysiological recordings from many neurons
simultaneously across entire brain circuits but don't reveal cell type. Here, we develop a …
simultaneously across entire brain circuits but don't reveal cell type. Here, we develop a …
Electrophysiological monitoring of neurochemical-based neural signal transmission in a human brain–spinal cord assembloid
Combining human brain organoids holds great potential in recapitulating the human brain's
histological features and modeling neural disorders. However, current combined-brain …
histological features and modeling neural disorders. However, current combined-brain …
Connecting circuits with networks in addiction neuroscience: A salience network perspective
Human neuroimaging has demonstrated the existence of large-scale functional networks in
the cerebral cortex consisting of topographically distant brain regions with functionally …
the cerebral cortex consisting of topographically distant brain regions with functionally …