Recent Advances in the Chemical Synthesis of C-Glycosides
Y Yang, B Yu - Chemical reviews, 2017 - ACS Publications
Advances in the chemical synthesis of C-pyranosides/furanosides are summarized, covering
the literature from 2000 to 2016. The majority of the methods take advantage of the …
the literature from 2000 to 2016. The majority of the methods take advantage of the …
Anodic oxidation for the stereoselective synthesis of heterocycles
K Yamamoto, M Kuriyama… - Accounts of Chemical …, 2019 - ACS Publications
Conspectus Stereodefined aliphatic heterocycles are one of the fundamental structural
motifs observed in natural products and biologically active compounds. Various strategies …
motifs observed in natural products and biologically active compounds. Various strategies …
Derivatization of carbohydrates for GC and GC–MS analyses
AI Ruiz-Matute, O Hernández-Hernández… - … of chromatography B, 2011 - Elsevier
GC and GC–MS are excellent techniques for the analysis of carbohydrates; nevertheless the
preparation of adequate derivatives is necessary. The different functional groups that can be …
preparation of adequate derivatives is necessary. The different functional groups that can be …
Iminosugars past, present and future: medicines for tomorrow
G Horne, FX Wilson, J Tinsley, DH Williams… - Drug discovery today, 2011 - Elsevier
Iminosugars comprise the most attractive class of carbohydrate mimetics reported to date
and are ideally positioned to take advantage of our increasing understanding of …
and are ideally positioned to take advantage of our increasing understanding of …
Iminosugars as therapeutic agents: recent advances and promising trends
For the purpose of this article, iminosugars are polyhydroxylated secondary and tertiary
amines in which the molecules resemble monosaccharide sugars in which the ring oxygen …
amines in which the molecules resemble monosaccharide sugars in which the ring oxygen …
Therapeutic significance of β-glucuronidase activity and its inhibitors: A review
The emergence of disease and dearth of effective pharmacological agents on most
therapeutic fronts, constitutes a major threat to global public health and man's existence …
therapeutic fronts, constitutes a major threat to global public health and man's existence …
Glycosphingolipids—nature, function, and pharmacological modulation
T Wennekes, RJ van den Berg, RG Boot… - Angewandte Chemie …, 2009 - Wiley Online Library
The discovery of the glycosphingolipids is generally attributed to Johan LW Thudichum, who
in 1884 published on the chemical composition of the brain. In his studies he isolated …
in 1884 published on the chemical composition of the brain. In his studies he isolated …
Design and synthesis of glycomimetics: Recent advances
A Tamburrini, C Colombo… - Medicinal research …, 2020 - Wiley Online Library
In the past few decades, our understanding of glycan information‐encoding power has
notably increased, thus leading to a significant growth also in the design and synthesis of …
notably increased, thus leading to a significant growth also in the design and synthesis of …
C− C bond-forming lyases in organic synthesis
M Brovetto, D Gamenara, P Saenz Mendez… - Chemical …, 2011 - ACS Publications
Lyases are enzymes that catalyze the bond construction and breaking by means other than
hydrolysis or redox reactions. Such enzymes are particular in the sense that they only …
hydrolysis or redox reactions. Such enzymes are particular in the sense that they only …
Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect
The electronic and structural properties of fullerene derivatives make them very attractive
candidates for the construction of nanostructures that are potentially useful for applications …
candidates for the construction of nanostructures that are potentially useful for applications …