Hydrogel adhesives for generalized wound treatment: Design and applications

M Li, G Pan, H Zhang, B Guo - Journal of Polymer Science, 2022 - Wiley Online Library
Wound refers to the place where human body is injured and ruptured. So, wounds in a
broad sense include not only skin wounds, but also damages of muscle, corneal, heart, and …

[HTML][HTML] The potential role of melatonin in retarding intervertebral disc ageing and degeneration: a systematic review

Z Cheng, Q **ang, J Wang, Y Zhang - Ageing Research Reviews, 2021 - Elsevier
Intervertebral disc degeneration (IDD) is a common degenerative disease of the
musculoskeletal system that develops with age. It is regarded as the main cause of chronic …

Tissue-mimetic hybrid bioadhesives for intervertebral disc repair

X Li, Y Liu, L Li, R Huo, F Ghezelbash, Z Ma, G Bao… - Materials …, 2023 - pubs.rsc.org
Intervertebral disc (IVD) degeneration and herniation often necessitate surgical interventions
including a discectomy with or without a nucleotomy, which results in a loss of the normal …

[HTML][HTML] Proper animal experimental designs for preclinical research of biomaterials for intervertebral disc regeneration

Y Peng, X Qing, H Shu, S Tian, W Yang… - Biomaterials …, 2021 - ncbi.nlm.nih.gov
Low back pain is a vital musculoskeletal disease that impairs life quality, leads to disability
and imposes heavy economic burden on the society, while it is greatly attributed to …

Sustained release of basic fibroblast growth factor in micro/nanofibrous scaffolds promotes annulus fibrosus regeneration

Z Tu, F Han, Z Zhu, Q Yu, C Liu, Y Bao, B Li, F Zhou - Acta Biomaterialia, 2023 - Elsevier
Tissue engineering has promising applications in the treatment of intervertebral disc
degeneration (IDD). The annulus fibrosus (AF) is critical for maintaining the physiological …

Composite Hydrogel Sealants for Annulus Fibrosus Repair

X Li, R Huo, L Li, H Cherif, X Lan… - ACS Biomaterials …, 2024 - ACS Publications
Intervertebral disc (IVD) herniation is a leading cause of disability and lower back pain,
causing enormous socioeconomic burdens. The standard of care for disc herniation is …

Genipin cross-linked decellularized nucleus pulposus hydrogel-like cell delivery system induces differentiation of ADSCs and retards intervertebral disc degeneration

L Yu, Y Liu, J Wu, S Wang, J Yu, W Wang… - … in Bioengineering and …, 2021 - frontiersin.org
Intervertebral disc degeneration (IDD) is the pathological basis of disc degenerative
diseases (DDD). Reduction in the number of cells and degeneration of the extracellular …

Recent advances in the repair of degenerative intervertebral disc for preclinical applications

Y Ying, K Cai, X Cai, K Zhang, R Qiu… - … in Bioengineering and …, 2023 - frontiersin.org
The intervertebral disc (IVD) is a load-bearing, avascular tissue that cushions pressure and
increases flexibility in the spine. Under the influence of obesity, injury, and reduced nutrient …

Chemonucleolysis combined with dynamic loading for inducing degeneration in bovine caudal intervertebral discs

A Vernengo, H Bumann, N Kluser… - … in Bioengineering and …, 2023 - frontiersin.org
Chemonucleolysis has become an established method of producing whole organ culture
models of intervertebral disc (IVD) degeneration. However, the field needs more side-by …

Mechanical stimulation promotes MSCs healing the lesion of intervertebral disc annulus fibrosus

R Deng, R Kang, X **, Z Wang, X Liu… - … in Bioengineering and …, 2023 - frontiersin.org
Mesenchymal stem cells (MSCs) and scaffolds offer promising perspectives for annulus
fibrosus (AF) repair. The repair effect was linked to features of the local mechanical …