Potassium channels are particularly important in determining the shape and duration of the
action potential, controlling the membrane potential, modulating hormone secretion …

Different calcium signals in the endothelium and smooth muscle target different types of
Ca2+-sensitive K+ channels to modulate vascular function. These differential calcium …

Abstract Ca2+-activated K+ (KCa) channels of small (SK) and intermediate (IK) conductance
are present in a wide range of excitable and non-excitable cells. On activation by low …

Potassium channels belong to the largest and the most diverse super-families of ion
channels. Among them, Ca 2+-activated K+ channels (KCa) comprise many members …

Urethane is widely used in neurophysiological experiments to anesthetize animals, yet little
is known about its actions at the cellular and synaptic levels. This limits our ability to model …

A proper rate of programmed cell death or apoptosis is required to maintain normal tissue
homeostasis. In disease states such as cancer and some forms of hypertension, apoptosis is …

Small conductance calcium-activated potassium (SK2/K Ca 2.2) channels are known to be
located in the neuronal plasma membrane where they provide feedback control of NMDA …

Activation of small conductance calcium-activated potassium (K Ca 2) channels can regulate
neuronal firing and synaptic plasticity. They are characterized by their high sensitivity to the …

Ion channels are transmembrane structures that allow the passage of ions across cell
membranes such as the plasma membrane or the membranes of various organelles like the …

The intermediate (IKCa) and small (SKCa) conductance Ca2+-sensitive K+ channels in
endothelial cells (ECs) modulate vascular diameter through regulation of EC membrane …