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Safety and clinical usage of Newcastle disease virus in cancer therapy
HY Lam, SK Yeap, M Rasoli, AR Omar… - BioMed Research …, 2011 - Wiley Online Library
Newcastle disease virus (NDV) is an avian virus that causes deadly infection to over 250
species of birds, including domestic and wild‐type, thus resulting in substantial losses to the …
species of birds, including domestic and wild‐type, thus resulting in substantial losses to the …
[HTML][HTML] Structural basis of targeting the exportin CRM1 in cancer
A Dickmanns, T Monecke, R Ficner - Cells, 2015 - mdpi.com
Recent studies have demonstrated the interference of nucleocytoplasmic trafficking with the
establishment and maintenance of various cancers. Nucleocytoplasmic transport is highly …
establishment and maintenance of various cancers. Nucleocytoplasmic transport is highly …
High-content assays for characterizing the viability and morphology of 3D cancer spheroid cultures
O Sirenko, T Mitlo, J Hesley, S Luke… - Assay and drug …, 2015 - liebertpub.com
There is an increasing interest in using three-dimensional (3D) spheroids for modeling
cancer and tissue biology to accelerate translation research. Development of higher …
cancer and tissue biology to accelerate translation research. Development of higher …
Cytotoxic effects of Mangifera indica L. kernel extract on human breast cancer (MCF-7 and MDA-MB-231 cell lines) and bioactive constituents in the crude extract
Abstract Background Waterlily Mango (Mangifera indica L.) is thought to be antioxidant-rich,
conferred by its functional phytochemicals. Methods The potential anticancer effects of the …
conferred by its functional phytochemicals. Methods The potential anticancer effects of the …
Zinc (II) coordination compound with N′-(pyridin-2-ylmethylene) nicotinohydrazide: Synthesis, crystal structure, computational and cytotoxicity studies
In this work, we report on the synthesis of a novel zinc (II) coordination compound [ZnL 2](1),
which was readily obtained from the reaction of Zn (OAc)· 2H 2 O and N′-(pyridin-2 …
which was readily obtained from the reaction of Zn (OAc)· 2H 2 O and N′-(pyridin-2 …
[HTML][HTML] In vitro cytotoxic activity of methanol extracts of selected medicinal plants traditionally used in Mexico against human hepatocellular carcinoma
Medicinal plants are traditionally used in Mexico to treat diseases such as cancer. The
present study aimed to evaluate the cytotoxic, antioxidant, and anti-hemolytic activity of 15 …
present study aimed to evaluate the cytotoxic, antioxidant, and anti-hemolytic activity of 15 …
[HTML][HTML] Anti-Cancer and Anti-Inflammatory Activities of a Short Molecule, PS14 Derived from the Virulent Cellulose Binding Domain of Aphanomyces invadans, on …
In this study, the anti-cancer and anti-inflammatory activities of PS14, a short peptide derived
from the cellulase binding domain of pathogenic fungus, Aphanomyces invadans, have …
from the cellulase binding domain of pathogenic fungus, Aphanomyces invadans, have …
Phenotypic characterization of toxic compound effects on liver spheroids derived from iPSC using confocal imaging and three-dimensional image analysis
O Sirenko, MK Hancock, J Hesley, D Hong… - Assay and drug …, 2016 - liebertpub.com
Cell models are becoming more complex to better mimic the in vivo environment and
provide greater predictivity for compound efficacy and toxicity. There is an increasing interest …
provide greater predictivity for compound efficacy and toxicity. There is an increasing interest …
Anticancer and apoptotic effects on cell proliferation of diosgenin isolated from Costus speciosus (Koen.) Sm
Background Diosgenin, a naturally occurring steroid saponin found abundantly in C.
speciosus, is a well-known precursor of various synthetic steroidal drugs that are extensively …
speciosus, is a well-known precursor of various synthetic steroidal drugs that are extensively …
Cytotoxic, Anti-Hemolytic, and Antioxidant Activities of Ruta chalepensis L. (Rutaceae) Extract, Fractions, and Isolated Compounds
Ruta chalepensis is an herb used to treat various ailments, and its potential cytotoxic effects
on different tumor cell lines have been extensively studied. The present study aimed to …
on different tumor cell lines have been extensively studied. The present study aimed to …