The concept of immune privilege suggests that the central nervous system is isolated from
the immune system. However, recent studies have highlighted the borders of the central …

Since its recent discovery, the meningeal lymphatic system has reshaped our understanding
of central nervous system (CNS) fluid exchange, waste clearance, immune cell trafficking …

Recent research in neuroimmunology has revolutionized our understanding of the intricate
interactions between the immune system and the central nervous system (CNS). The CNS …

The term “glymphatic” emerged roughly a decade ago, marking a pivotal point in
neuroscience research. The glymphatic system, a glial-dependent perivascular network …

Cerebral ischemia is a devastating condition that results in impaired blood flow in the brain
leading to acute brain injury. As the most common form of stroke, occlusion of cerebral …

Reelin, an extracellular matrix protein with putative antidepressant-like properties, becomes
dysregulated by chronic stress. Improvement in cognitive dysfunction and depression-like …

Age-related cognitive decline is associated with dysfunctional lymphatic drainage of
cerebrospinal fluid (CSF) through meningeal lymphatic vessels. In this study, intrathecal …

Due to the increased crewed spaceflights in recent years, it is vital to understand how the
space environment affects human health. A lack of gravitational force is known to risk …

Lymphatic aging represented by cellular and functional changes, is involved in increased
geriatric disorders, but the intersection between aging and lymphatic modulation is less …

Meningeal lymphatic vessels form a relationship between the nervous system and
periphery, which is relevant in both health and disease. Meningeal lymphatic vessels not …