Ferroptosis as a mechanism of non-ferrous metal toxicity

M Aschner, AV Skalny, AC Martins, AI Sinitskii… - Archives of …, 2022‏ - Springer
Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …

[HTML][HTML] Plant polyphenol antioxidants and oxidative stress

I Urquiaga, F Leighton - Biological research, 2000‏ - SciELO Chile
In recent years there has been a remarkable increment in scientific articles dealing with
oxidative stress. Several reasons justify this trend: knowledge about reactive oxygen and …

Zinc and the modulation of redox homeostasis

PI Oteiza - Free Radical Biology and Medicine, 2012‏ - Elsevier
Zinc, a redox-inactive metal, has been long viewed as a component of the antioxidant
network, and growing evidence points to its involvement in redox-regulated signaling. These …

Comparative study on the inhibitory effect of caffeic and chlorogenic acids on key enzymes linked to Alzheimer's disease and some pro-oxidant induced oxidative …

G Oboh, OM Agunloye, AJ Akinyemi… - Neurochemical …, 2013‏ - Springer
This study sought to investigate and compare the interaction of caffeic acid and chlorogenic
acid on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), and some pro …

Flavonoid‐membrane interactions: A protective role of flavonoids at the membrane surface?

PI Oteiza, AG Erlejman, SV Verstraeten… - Journal of …, 2005‏ - Wiley Online Library
Flavonoids can exert beneficial health effects through multiple mechanisms. In this paper,
we address the important, although not fully understood, capacity of flavonoids to interact …

The antioxidant properties of zinc: interactions with iron and antioxidants

MP Zago, PI Oteiza - Free Radical Biology and Medicine, 2001‏ - Elsevier
Potential mechanisms underlying zinc's capacity to protect membranes from lipid oxidation
were examined in liposomes. Using lipid oxidation initiators with different chemical and …

Zinc deficiency as a possible risk factor for increased susceptibility and severe progression of Corona Virus Disease 19

I Wessels, B Rolles, AJ Slusarenko… - British journal of Nutrition, 2022‏ - cambridge.org
The importance of Zn for human health becomes obvious during Zn deficiency. Even mild
insufficiencies of Zn cause alterations in haematopoiesis and immune functions, resulting in …

Iron toxicity and antioxidant nutrients

CG Fraga, PI Oteiza - Toxicology, 2002‏ - Elsevier
Iron is an essential nutrient for the growth, development, and long-term survival of most
organisms. High tissue iron concentrations have been associated with the development and …

Hot pepper (Capsicum annuum, Tepin and Capsicum chinese, Habanero) prevents Fe2+-induced lipid peroxidation in brain–in vitro

G Oboh, RL Puntel, JBT Rocha - Food chemistry, 2007‏ - Elsevier
Iron is an essential metal for normal cellular physiology, but excess iron results in cell injury;
it reacts with superoxide anions (O2) and hydrogen peroxide (H2O2) to produce the …

The oxidative stress of zinc deficiency

DJ Eide - Metallomics, 2011‏ - academic.oup.com
Zinc is an essential catalytic and structural cofactor for many enzymes and other proteins.
While Zn2+ is not redox active under physiological conditions, it has been known for many …