Bioactive compounds in oxidative stress-mediated diseases: targeting the NRF2/ARE signaling pathway and epigenetic regulation

M Thiruvengadam, B Venkidasamy, U Subramanian… - Antioxidants, 2021‏ - mdpi.com
Oxidative stress is a pathological condition occurring due to an imbalance between the
oxidants and antioxidant defense systems in the body. Nuclear factor E2-related factor 2 …

Role of endogenous lipopolysaccharides in neurological disorders

M Kalyan, AH Tousif, S Sonali, C Vichitra, T Sunanda… - Cells, 2022‏ - mdpi.com
Lipopolysaccharide (LPS) is a cell-wall immunostimulatory endotoxin component of Gram-
negative bacteria. A growing body of evidence reveals that alterations in the bacterial …

Diet and lifestyle impact the development and progression of Alzheimer's dementia

S Arora, JA Santiago, M Bernstein… - Frontiers in nutrition, 2023‏ - frontiersin.org
Dementia is a growing public health concern, with an estimated prevalence of 57 million
adults worldwide. Alzheimer's disease (AD) accounts for 60–80% of the cases. Clinical trials …

The role of natural products in revealing NRF2 function

DD Zhang, E Chapman - Natural product reports, 2020‏ - pubs.rsc.org
Covering: up to 2020 The transcription factor NRF2 is one of the body's major defense
mechanisms, driving transcription of> 300 antioxidant response element (ARE)-regulated …

Mechanism of action of certain medicinal plants for the treatment of asthma

K Usmani, SK Jain, S Yadav - Journal of Ethnopharmacology, 2023‏ - Elsevier
Ethnopharmacological relevance Asthma is often treated and prevented using the
pharmacological properties of traditional medicinal plants. These healthcare systems are …

Anti-Alzheimer, anti-diabetic, skin-whitening, and antioxidant activities of the essential oil of Cinnamomum zeylanicum

AS Tepe, M Ozaslan - Industrial Crops and Products, 2020‏ - Elsevier
This study was designed to determine the anti-Alzheimer, anti-diabetic, skin whitening, and
antioxidant activities of the essential oil of Cinnamomum zeylanicum (Blume) as well as the …

[HTML][HTML] Anti-viral potential and modulation of Nrf2 by curcumin: pharmacological implications

M Rahban, M Habibi-Rezaei, M Mazaheri, L Saso… - Antioxidants, 2020‏ - mdpi.com
Nuclear factor erythroid 2-related factor 2 (Nrf2) is an essential transcription factor that
maintains the cell's redox balance state and reduces inflammation in different adverse …

[HTML][HTML] Role of Nrf2 in synaptic plasticity and memory in Alzheimer's disease

DA Davies, A Adlimoghaddam, BC Albensi - Cells, 2021‏ - mdpi.com
Nuclear factor erythroid 2-related factor 2 (Nrf2) is an important transcription factor that
reduces oxidative stress. When reactive oxygen species (ROS) or reactive nitrogen species …

Electrospun anti-inflammatory patch loaded with essential oils for wound healing

S Garcia-Salinas, M Evangelopoulos… - International journal of …, 2020‏ - Elsevier
Wound healing is a complex process that consists of three overlap** phases:
inflammation, proliferation, and remodeling. A bacterial infection can increase inflammation …

Non-polyphenolic natural inhibitors of amyloid aggregation

L Ma, C Yang, J Zheng, Y Chen, Y **ao… - European journal of …, 2020‏ - Elsevier
Protein misfolding diseases (PMDs) are chronic and progressive, with no effective therapy
so far. Aggregation and misfolding of amyloidogenic proteins are closely associated with the …