HDL and reverse cholesterol transport: Basic mechanisms and their roles in vascular health and disease

M Ouimet, TJ Barrett, EA Fisher - Circulation research, 2019 - ahajournals.org
Cardiovascular disease, with atherosclerosis as the major underlying factor, remains the
leading cause of death worldwide. It is well established that cholesterol ester-enriched foam …

High-density lipoprotein (HDL) functionality and its relevance to atherosclerotic cardiovascular disease

CE Kosmas, I Martinez, A Sourlas, KV Bouza… - Drugs in …, 2018 - pmc.ncbi.nlm.nih.gov
Several prospective epidemiological studies have shown that there is a clear inverse
relationship between serum high-density lipoprotein-cholesterol (HDL-C) concentrations …

RAGE signaling regulates the progression of diabetic complications

K Taguchi, K Fukami - Frontiers in Pharmacology, 2023 - frontiersin.org
Diabetes, the ninth leading cause of death globally, is expected to affect 642 million people
by 2040. With the advancement of an aging society, the number of patients with diabetes …

Diabetic fibrosis

I Tuleta, NG Frangogiannis - … et Biophysica Acta (BBA)-Molecular Basis of …, 2021 - Elsevier
Diabetes-associated morbidity and mortality is predominantly due to complications of the
disease that may cause debilitating conditions, such as heart and renal failure, hepatic …

[HTML][HTML] Lipids and lipoproteins in cardiovascular diseases: a classification

S Bhargava, S De la Puente-Secades… - Trends in Endocrinology …, 2022 - cell.com
Lipids and lipoproteins, their metabolism, and their transport are essential contributing
factors of cardiovascular disease (CVD) as they regulate plasma cholesterol concentration …

Fibrosis of the diabetic heart: Clinical significance, molecular mechanisms, and therapeutic opportunities

I Tuleta, NG Frangogiannis - Advanced drug delivery reviews, 2021 - Elsevier
In patients with diabetes, myocardial fibrosis may contribute to the pathogenesis of heart
failure and arrhythmogenesis, increasing ventricular stiffness and delaying conduction …

Advanced glycation end-products: a review

R Singh, A Barden, T Mori, L Beilin - Diabetologia, 2001 - Springer
Advanced glycation end-products are a complex and heterogeneous group of compounds
that have been implicated in diabetes related complications. At present it is not known if they …

Advanced glycation endproducts—role in pathology of diabetic complications

N Ahmed - Diabetes research and clinical practice, 2005 - Elsevier
Diabetes mellitus is a common endocrine disorder characterised by hyperglycaemia and
predisposes to chronic complications affecting the eyes, blood vessels, nerves and kidneys …

The functional role of lipoproteins in atherosclerosis: novel directions for diagnosis and targeting therapy

Y Lu, X Cui, L Zhang, X Wang, Y Xu, Z Qin… - Aging and …, 2022 - pmc.ncbi.nlm.nih.gov
Dyslipidemia, characterized by a high level of lipids (cholesterol, triglycerides, or both), can
increase the risk of develo** and progressing atherosclerosis. As atherosclerosis …

The role and function of HDL in patients with diabetes mellitus and the related cardiovascular risk

M Femlak, A Gluba-Brzózka… - Lipids in health and …, 2017 - Springer
Background Diabetes mellitus (DM) is a major public health problem which prevalence is
constantly raising, particularly in low-and middle-income countries. Both diabetes mellitus …