Diagnosis of Alzheimer's disease utilizing amyloid and tau as fluid biomarkers

JC Lee, SJ Kim, S Hong, YS Kim - Experimental & molecular medicine, 2019 - nature.com
Current technological advancements in clinical and research settings have permitted a more
intensive and comprehensive understanding of Alzheimer's disease (AD). This development …

Mechanisms of short-chain fatty acids derived from gut microbiota in Alzheimer's disease

X Qian, R **e, X Liu, H Tang - Aging and disease, 2022 - pmc.ncbi.nlm.nih.gov
Short-chain fatty acids (SCFAs) are important metabolites derived from the gut microbiota
through fermentation of dietary fiber. SCFAs participate a number of physiological and …

A multiomics approach to heterogeneity in Alzheimer's disease: focused review and roadmap

AP Badhwar, GP McFall, S Sapkota, SE Black… - Brain, 2020 - academic.oup.com
Aetiological and clinical heterogeneity is increasingly recognized as a common
characteristic of Alzheimer's disease and related dementias. This heterogeneity complicates …

[HTML][HTML] Methylsulfonylmethane: applications and safety of a novel dietary supplement

M Butawan, RL Benjamin, RJ Bloomer - Nutrients, 2017 - mdpi.com
Methylsulfonylmethane (MSM) has become a popular dietary supplement used for a variety
of purposes, including its most common use as an anti-inflammatory agent. It has been well …

[HTML][HTML] Salivary metabolomics: from diagnostic biomarker discovery to investigating biological function

A Gardner, G Carpenter, PW So - Metabolites, 2020 - mdpi.com
Metabolomic profiling of biofluids, eg, urine, plasma, has generated vast and ever-
increasing amounts of knowledge over the last few decades. Paradoxically, metabolomic …

[HTML][HTML] Biological and environmental predictors of heterogeneity in neurocognitive ageing: Evidence from Betula and other longitudinal studies

L Nyberg, CJ Boraxbekk, DE Sörman, P Hansson… - Ageing research …, 2020 - Elsevier
Individual differences in cognitive performance increase with advancing age, reflecting
marked cognitive changes in some individuals along with little or no change in others …

Metabolomics technology and bioinformatics for precision medicine

RK Azad, V Shulaev - Briefings in bioinformatics, 2019 - academic.oup.com
Precision medicine is rapidly emerging as a strategy to tailor medical treatment to a small
group or even individual patients based on their genetics, environment and lifestyle …

Roles of taurine in cognitive function of physiology, pathologies and toxication

C Chen, SF **a, J He, G Lu, Z **e, H Han - Life Sciences, 2019 - Elsevier
Taurine is a key functional amino acid with many functions in the nervous system. The
effects of taurine on cognitive function have aroused increasing attention. First, the …

Dietary fiber modulates the release of gut bacterial products preventing cognitive decline in an Alzheimer's mouse model

D Cuervo-Zanatta, T Syeda, V Sánchez-Valle… - Cellular and Molecular …, 2023 - Springer
Fiber intake is associated with a lower risk for Alzheimer´ s disease (AD) in older adults.
Intake of plant-based diets rich in soluble fiber promotes the production of short-chain fatty …

Applied machine learning in Alzheimer's disease research: omics, imaging, and clinical data

Z Li, X Jiang, Y Wang, Y Kim - Emerging topics in life sciences, 2021 - portlandpress.com
Alzheimer's disease (AD) remains a devastating neurodegenerative disease with few
preventive or curative treatments available. Modern technology developments of high …