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Trial watch: chemotherapy-induced immunogenic cell death in oncology
Immunogenic cell death (ICD) refers to an immunologically distinct process of regulated cell
death that activates, rather than suppresses, innate and adaptive immune responses. Such …
death that activates, rather than suppresses, innate and adaptive immune responses. Such …
Trial watch: Dendritic cell (DC)-based immunotherapy for cancer
Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable
development over recent decades. However, this field is currently in a state of flux toward …
development over recent decades. However, this field is currently in a state of flux toward …
[HTML][HTML] The interface of tumour-associated macrophages with dying cancer cells in immuno-oncology
Tumour-associated macrophages (TAMs) are essential players in the tumour
microenvironment (TME) and modulate various pro-tumorigenic functions such as …
microenvironment (TME) and modulate various pro-tumorigenic functions such as …
Peripheral gene signatures reveal distinct cancer patient immunotypes with therapeutic implications for autologous DC-based vaccines
M Hensler, J Rakova, L Kasikova, T Lanickova… - …, 2022 - Taylor & Francis
Dendritic cells (DCs) have received considerable attention as potential targets for the
development of novel cancer immunotherapies. However, the clinical efficacy of DC-based …
development of novel cancer immunotherapies. However, the clinical efficacy of DC-based …
Circulating biomarkers at diagnosis correlate with distant metastases of early luminal-like breast cancer
There is an urgent need for new and better biomarker modalities to estimate the risk of
recurrence within the luminal-like breast cancer (BC) population. Molecular diagnostic tests …
recurrence within the luminal-like breast cancer (BC) population. Molecular diagnostic tests …
Dissection of molecular determinants of metastasis and detailed characterization of the age-related immunological profile in (older) patients with hormone-sensitive …
Y Lambrechts, H Wildiers, G Floris, S Hatse - 2023 - lirias.kuleuven.be
This PhD project's main objective is to better understand and characterize the tumor biology
and immunology of HR+/HER2-breast cancer in (older) patients. First, we want to improve …
and immunology of HR+/HER2-breast cancer in (older) patients. First, we want to improve …