Polyester based polymeric nano and microparticles for pharmaceutical purposes: A review on formulation approaches

F Molavi, M Barzegar-Jalali, H Hamishehkar - Journal of Controlled …, 2020‏ - Elsevier
The novel polymeric particulate systems show high potential in their clinical effectiveness.
Nevertheless, many of the drug delivery systems developed in the research laboratories …

[HTML][HTML] Application of starch, cellulose, and their derivatives in the development of microparticle drug-delivery systems

P Lukova, P Katsarov, B Pilicheva - Polymers, 2023‏ - mdpi.com
Micro-and nanotechnologies have been intensively studied in recent years as novel
platforms for targeting and controlling the delivery of various pharmaceutical substances …

[HTML][HTML] Pulmonary inhalation for disease treatment: Basic research and clinical translations

B Wang, L Wang, Q Yang, Y Zhang, T Qinglai, X Yang… - Materials Today Bio, 2024‏ - Elsevier
Pulmonary drug delivery has the advantages of being rapid, efficient, and well-targeted, with
few systemic side effects. In addition, it is non-invasive and has good patient compliance …

A comprehensive overview of dry powder inhalers for pulmonary drug delivery: Challenges, advances, optimization techniques, and applications

HI Shahin, L Chablani - Journal of Drug Delivery Science and Technology, 2023‏ - Elsevier
Dry powder inhaler (DPI) is an attractive dosage form for local and systemic pulmonary drug
delivery. However, designing DPIs with adequate physicochemical properties is …

Recent advances in cellulose microgels: preparations and functionalized applications

Y Yang, L Sha, H Zhao, Z Guo, M Wu, P Lu - Advances in Colloid and …, 2023‏ - Elsevier
Microgels are soft, deformable, permeable, and stimuli-responsive microscopic polymeric
particles that are now emerging as prospective multifunctional soft materials for delivery …

Formulation and evaluation of inhaled Sildenafil-loaded PLGA microparticles for treatment of pulmonary arterial hypertension (PAH): A novel high drug loaded …

M Almutairi, A Hefnawy, A Almotairy, A Alobaida… - International Journal of …, 2024‏ - Elsevier
In recent years, several techniques were employed to develop a local sustained pulmonary
delivery of sildenafil citrate (SC) as an alternative for the intravenous and oral treatment of …

Hyaluronic acid hydrogels for controlled pulmonary drug delivery—a particle engineering approach

D Nikjoo, I van der Zwaan, M Brülls, U Tehler… - Pharmaceutics, 2021‏ - mdpi.com
Hydrogels warrant attention as a potential material for use in sustained pulmonary drug
delivery due to their swelling and mucoadhesive features. Herein, hyaluronic acid (HA) is …

Targeted delivery of baicalein-p53 complex to smooth muscle cells reverses pulmonary hypertension

C Teng, B Li, C Lin, X **ng, F Huang, Y Yang… - Journal of Controlled …, 2022‏ - Elsevier
Pulmonary arterial hypertension (PAH) is an uncommon and deadly cardiopulmonary
disease. PAH stems essentially from pulmonary artery (PA) remodeling induced …

Polysaccharide-based formulations as potential carriers for pulmonary delivery–a review of their properties and fates

SA Valente, LM Silva, GR Lopes, B Sarmento… - Carbohydrate …, 2022‏ - Elsevier
Polysaccharides can be elite carriers for therapeutic molecules due to their versatility and
low probability to trigger toxicity and immunogenic responses. Local and systemic therapies …

[HTML][HTML] A dry powder platform for nose-to-brain delivery of dexamethasone: formulation development and nasal deposition studies

L Nižić Nodilo, I Ugrina, D Špoljarić, D Amidžić Klarić… - Pharmaceutics, 2021‏ - mdpi.com
Nasal route of administration offers a unique opportunity of brain targeted drug delivery via
olfactory and trigeminal pathway, providing effective CNS concentrations at lower doses and …