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Cross-linking mass spectrometry for investigating protein conformations and protein–protein Interactions─ A method for all seasons
Mass spectrometry (MS) has become one of the key technologies of structural biology. In this
review, the contributions of chemical cross-linking combined with mass spectrometry (XL …
review, the contributions of chemical cross-linking combined with mass spectrometry (XL …
Recommendations for reporting ion mobility Mass Spectrometry measurements
Here we present a guide to ion mobility mass spectrometry experiments, which covers both
linear and nonlinear methods: what is measured, how the measurements are done, and how …
linear and nonlinear methods: what is measured, how the measurements are done, and how …
Mass spectrometry-based protein footprinting for higher-order structure analysis: fundamentals and applications
Proteins adopt different higher-order structures (HOS) to enable their unique biological
functions. Understanding the complexities of protein higher-order structures and dynamics …
functions. Understanding the complexities of protein higher-order structures and dynamics …
Cross-linking mass spectrometry (XL-MS): an emerging technology for interactomics and structural biology
Protein-protein interactions are fundamental to the formation of intricate interaction networks
and the assembly of multisubunit protein complexes that represent the functional …
and the assembly of multisubunit protein complexes that represent the functional …
Protein–small molecule interactions in native mass spectrometry
Small molecule drug discovery has been propelled by the continual development of novel
scientific methodologies to occasion therapeutic advances. Although established …
scientific methodologies to occasion therapeutic advances. Although established …
Identification of carbohydrate anomers using ion mobility–mass spectrometry
Carbohydrates are ubiquitous biological polymers that are important in a broad range of
biological processes,,. However, owing to their branched structures and the presence of …
biological processes,,. However, owing to their branched structures and the presence of …
Characterization of therapeutic antibodies and related products
Here, we review the current state of the art in analytical and structural methods used to
characterize therapeutic monoclonal antibodies (mAbs) and derivatives. First, a general …
characterize therapeutic monoclonal antibodies (mAbs) and derivatives. First, a general …
Collision cross sections of proteins and their complexes: a calibration framework and database for gas-phase structural biology
Collision cross sections in both helium and nitrogen gases were measured directly using a
drift cell with RF ion confinement inserted within a quadrupole/ion mobility/time-of-flight …
drift cell with RF ion confinement inserted within a quadrupole/ion mobility/time-of-flight …
[كتاب][B] Ion mobility spectrometry
GA Eiceman, Z Karpas - 2005 - taylorfrancis.com
Key Developments for Faster, More Precise Detection Capabilities Driven by the demand for
the rapid and advanced detection of explosives, chemical and biological warfare agents …
the rapid and advanced detection of explosives, chemical and biological warfare agents …
Collision cross sections for structural proteomics
Ion mobility mass spectrometry (IM-MS) allows the structural interrogation of biomolecules
by reporting their collision cross sections (CCSs). The major bottleneck for exploiting IM-MS …
by reporting their collision cross sections (CCSs). The major bottleneck for exploiting IM-MS …