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Digital twins for multiple sclerosis
I Voigt, H Inojosa, A Dillenseger, R Haase… - Frontiers in …, 2021 - frontiersin.org
An individualized innovative disease management is of great importance for people with
multiple sclerosis (pwMS) to cope with the complexity of this chronic, multidimensional …
multiple sclerosis (pwMS) to cope with the complexity of this chronic, multidimensional …
Digital biomarkers in multiple sclerosis
A Dillenseger, ML Weidemann, K Trentzsch, H Inojosa… - Brain sciences, 2021 - mdpi.com
For incurable diseases, such as multiple sclerosis (MS), the prevention of progression and
the preservation of quality of life play a crucial role over the entire therapy period. In MS …
the preservation of quality of life play a crucial role over the entire therapy period. In MS …
Lesion network localization of depression in multiple sclerosis
Multiple sclerosis (MS), a demyelinating disease that causes focal white matter lesions, is
commonly associated with depression. However, it remains unclear whether depression risk …
commonly associated with depression. However, it remains unclear whether depression risk …
Management of multiple sclerosis fatigue in the digital age: From assessment to treatment
C Pinarello, J Elmers, H Inojosa, C Beste… - Frontiers in …, 2023 - frontiersin.org
Fatigue is one of the most disabling symptoms of Multiple Sclerosis (MS), affecting more
than 80% of patients over the disease course. Nevertheless, it has a multi-faceted and …
than 80% of patients over the disease course. Nevertheless, it has a multi-faceted and …
No increase in symptoms toward the end of the ocrelizumab infusion cycle in patients with multiple sclerosis: symptom burden on ocrelizumab: a longitudinal study …
I Kister, C Oh, EA Douglas, TE Bacon… - Neurology: Clinical …, 2023 - AAN Enterprises
Background and Objectives Some patients with multiple sclerosis (MS) receiving
ocrelizumab (OCR) report worsening symptoms toward the end of the 6-month infusion cycle …
ocrelizumab (OCR) report worsening symptoms toward the end of the 6-month infusion cycle …
A novel digital care management platform to monitor clinical and subclinical disease activity in multiple sclerosis
W Van Hecke, L Costers, A Descamps, A Ribbens… - Brain sciences, 2021 - mdpi.com
In multiple sclerosis (MS), the early detection of disease activity or progression is key to
inform treatment changes and could be supported by digital tools. We present a novel CE …
inform treatment changes and could be supported by digital tools. We present a novel CE …
Data collection in multiple sclerosis: the MSDS approach
T Ziemssen, R Kern, I Voigt, R Haase - Frontiers in Neurology, 2020 - frontiersin.org
Multiple sclerosis (MS) is a frequent chronic inflammatory disease of the central nervous
system that affects patients over decades. As the monitoring and treatment of MS become …
system that affects patients over decades. As the monitoring and treatment of MS become …
Latent structure of a brief clinical battery of neuropsychological tests administered in-home via telephone
Objective To examine the factor structure and sociodemographic correlates of a battery of
clinical neuropsychological tests administered in-home and via telephone. Method …
clinical neuropsychological tests administered in-home and via telephone. Method …
Outcome measures for physical fatigue in individuals with multiple sclerosis: a systematic review
G Sellitto, A Morelli, S Bassano, A Conte… - Expert Review of …, 2021 - Taylor & Francis
Introduction Physical fatigue can be a common reason for early retirement or sick leave
since it appears in the earliest stages of multiple sclerosis (MS). Therefore, a prompt and …
since it appears in the earliest stages of multiple sclerosis (MS). Therefore, a prompt and …
Establishing clinically meaningful within-individual improvement thresholds for eight patient-reported outcome measures in people with relapsing-remitting multiple …
N Greene, S Quéré, DP Bury, F Mazerolle… - Journal of Patient …, 2023 - Springer
Background As disease-modifying therapies do not reverse the course of multiple sclerosis
(MS), assessment of therapeutic success involves documenting patient-reported outcomes …
(MS), assessment of therapeutic success involves documenting patient-reported outcomes …