[HTML][HTML] Classification of uremic toxins and their role in kidney failure

MH Rosner, T Reis, F Husain-Syed… - Clinical Journal of the …, 2021 - journals.lww.com
Advances in our understanding of uremic retention solutes, and improvements in
hemodialysis membranes and other techniques designed to remove uremic retention …

Effects of expanded hemodialysis with medium cut-off membranes on maintenance hemodialysis patients: a review

Z Zhang, T Yang, Y Li, J Li, Q Yang, L Wang, L Jiang… - Membranes, 2022 - mdpi.com
Kidney failure is associated with high morbidity and mortality. Hemodialysis, the most
prevalent modality of renal replacement therapy, uses the principle of semipermeable …

Efficacy and safety of expanded hemodialysis with the theranova 400 dialyzer: a randomized controlled trial

DE Weiner, L Falzon, L Skoufos… - Clinical Journal of the …, 2020 - journals.lww.com
Results Among 172 patients on maintenance hemodialysis, mean age was 59±13 years,
61% were men, 40% were Black, and mean dialysis vintage was 5±4 years. Of the 86 …

Comparison of four medium cut-off dialyzers

F Maduell, JJ Broseta… - Clinical Kidney …, 2022 - academic.oup.com
Background Recently, several pharmaceutical companies have developed new medium cut-
off (MCO) dialyzers for expanded hemodialysis (HDx). This study aimed to compare the …

A trial evaluating mid cut-off value membrane clearance of albumin and light chains in hemodialysis patients: a safety device study

R Krishnasamy, CM Hawley, MJ Jardine… - Blood purification, 2020 - karger.com
Background: A new class of dialysis membrane, the mid cut-off (MCO) dialyzer, has been
developed to improve the clearance of uremic toxins in hemodialysis (HD). The a tRial …

Continuous renal replacement therapy and extended indications

C Ronco, T Reis - Seminars in dialysis, 2021 - Wiley Online Library
Extracorporeal blood purification (EBP) techniques provide support for critically ill patients
with single or multiple organ dysfunction. Continuous renal replacement therapy (CRRT) is …

Comparison of circulating levels of uremic toxins in hemodialysis patients treated with medium cut-off membranes and high-flux membranes: Theranova in Sisli …

M Sevinc, NB Hasbal, V Yilmaz, T Basturk, E Ahbap… - Blood …, 2020 - karger.com
Introduction: Removal of uremic toxins is a main objective of hemodialysis; however,
whether high-flux and medium cut-off (MCO) membranes differ as regards removal of middle …

Rationale for a new classification of solutes of interest in chronic kidney disease and hemodialysis

T Reis, C Hutchison, F de Assis Rocha Neves… - Blood …, 2023 - karger.com
A hallmark of chronic kidney disease is the retention of solutes that normally are eliminated
by the kidneys. The current classification defines uremic toxins based on molecular weight …

Mass transport in high-flux hemodialysis: application of engineering principles to clinical prescription

F Mohajerani, WR Clark, C Ronco… - Clinical Journal of the …, 2022 - journals.lww.com
An understanding of the processes underlying mass transfer is paramount for the attainment
of adequate solute removal in the dialytic treatment of patients with kidney failure. In this …

The medium cut-off membrane does not lower protein-bound uremic toxins

YG Kim, SH Lee, SW Jung, GT Jung, HJ Lim, KP Kim… - Toxins, 2022 - mdpi.com
The accumulation of protein-bound uremic toxins (PBUT) is associated with increased
cardiovascular outcomes in patients on dialysis. However, the efficacy of PBUT removal for a …