In industrialized countries, population wide cytological screening programs using the Pap
test have led to a substantial reduction of the incidence of cervical cancer. Despite this …

Similar to genetic alterations, epigenetic aberrations contribute significantly to tumor
initiation and progression. In many cases, these changes are caused by activation or …

The diagnosis of cancer and other diseases using data from non-specific sensors–such as
the electronic tongues (e-tongues)-is challenging owing to the lack of selectivity, in addition …

Cervical cancer (CC) cells exhibit complex karyotypic alterations, which is consistent with
deregulation of numerous critical genes in its formation and progression. To characterize …

The array CGH technique (Array Comparative Genome Hybridization) has been developed
to detect chromosomal copy number changes on a genome-wide and/or high-resolution …

Ubiquitin-dependent molecular chaperone p97, also known as valosin-containing protein
(VCP) or Cdc48, is an AAA ATPase involved in protein turnover and degradation. p97 …

For a better understanding of the consequences of recurrent chromosomal alterations in
cervical carcinomas, we integrated genome‐wide chromosomal and transcriptional profiles …

FAS-associated factor 1, FAF1, is an evolutionarily conserved protein that has several
protein interaction domains. Although FAF1 was initially identified as a member of the FAS …

Aberrant histone lysine methylation that is controlled by histone lysine methyltransferases
(KMTs) and demethylases (KDMs) plays significant roles in carcinogenesis. Infections by …

In the last decade, new molecular techniques were introduced into pathology laboratories.
Cytology also benefited from the innovations emerging from this new era. Molecular …