[HTML][HTML] Inflammation and cardiovascular disease: From mechanisms to therapeutics

A Alfaddagh, SS Martin, TM Leucker, ED Michos… - American journal of …, 2020 - Elsevier
Inflammation constitutes a complex, highly conserved cascade of molecular and cellular
events. Inflammation has been labeled as “the fire within,” is highly regulated, and is critical …

In silico methods for predicting functional synonymous variants

BC Lin, U Katneni, KI Jankowska, D Meyer… - Genome Biology, 2023 - Springer
Single nucleotide variants (SNVs) contribute to human genomic diversity. Synonymous
SNVs are previously considered to be “silent,” but mounting evidence has revealed that …

[HTML][HTML] MicroRNAs in the development of potential therapeutic targets against COVID-19: A narrative review

JQ Ahmed, SQ Maulud, M Dhawan… - Journal of Infection and …, 2022 - Elsevier
Background As the therapeutic regimens against the COVID-19 remain scarce, the
microRNAs (miRNAs) can be exploited to generate efficient therapeutic targets. The miRNAs …

M2 macrophage-derived exosomal miR-193b-3p promotes progression and glutamine uptake of pancreatic cancer by targeting TRIM62

K Zhang, YJ Li, LJ Peng, HF Gao, LM Liu, H Chen - Biology Direct, 2023 - Springer
Background Pancreatic cancer (PC) is a highly lethal malignancy that requires effective
novel therapies. M2 macrophages are abundant in the PC microenvironment and promote …

Quercetin and osteoarthritis: a mechanistic review on the present documents

F Samadi, MS Kahrizi, F Heydari, R Arefnezhad… - Pharmacology, 2022 - karger.com
Background: Osteoarthritis (OA), as one of the chronic debilitating conditions, affects 15% of
people globally and is linked with serious problems, such as cardiovascular diseases …

Circulating microRNAs as potential molecular biomarkers for intracranial aneurysmal rupture

M Supriya, R Christopher, B Indira Devi, DI Bhat… - Molecular Diagnosis & …, 2020 - Springer
Introduction Diagnosis of the rupture of an intracranial aneurysm (IA) relies on sophisticated
neuro-imaging studies, and molecular biomarkers to identify an IA or predict its rupture are …

Circular RNAs regulate cancer-related signaling pathways and serve as potential diagnostic biomarkers for human cancers

P Garlapati, J Ling, PJ Chiao, J Fu - Cancer Cell International, 2021 - Springer
Abstract Circular RNAs (circRNAs) are RNAs that have an important role in various
pathological processes, including cancer. After the usage of high-throughput RNA …

Identification of biomarkers for bull fertility using functional genomics

MR Ugur, DD Guerreiro, AA Moura, E Memili - Animal Reproduction, 2022 - SciELO Brasil
Prediction of bull fertility is critical for the sustainability of both dairy and beef cattle
production. Even though bulls produce ample amounts of sperm with normal parameters …

Current evidence on potential uses of MicroRNA biomarkers for migraine: from diagnosis to treatment

P Gazerani - Molecular diagnosis & therapy, 2019 - Springer
Migraine is a disabling and recurrent neurological disorder characterized by headache
attacks that are often accompanied by sensory and motor disturbances. The value and …

A systematic review of non-coding RNA genes with differential expression profiles associated with autism spectrum disorders

J Stott, T Wright, J Holmes, J Wilson, S Griffiths-Jones… - Plos one, 2023 - journals.plos.org
Aims To identify differential expression of shorter non-coding RNA (ncRNA) genes
associated with autism spectrum disorders (ASD). Background ncRNA are functional …