In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

Inflammation is a protective response of the body potentially caused by microbial, viral, or
fungal infections, tissue damage, or even autoimmune reactions. The cardinal signs of …

The recently identified ferroptotic cell death is characterized by excessive accumulation of
hydroperoxy-arachidonoyl (C20: 4)-or adrenoyl (C22: 4)-phosphatidylethanolamine (Hp …

The recent outbreak of Zika virus (ZIKV) was associated with birth defects and pregnancy
loss when maternal infection occurs in early pregnancy, but specific mechanisms driving …

Endogenous signaling molecules derived from lipids, peptides, and DNA, are important
regulators of physiological processes during pregnancy. The effect of their collective impact …

Prostaglandins (PGs) are lipid mediators belonging to the eicosanoid family. PGs were first
discovered in mammals where they are key players in a great variety of physiological and …

Human labour is an inflammatory event, physiologically driven by an interaction between
hormonal and mechanical factors and pathologically associated with infection, bleeding and …

Pregnancy complications including preeclampsia, preterm birth, intrauterine growth
restriction, and gestational diabetes are the main adverse reproductive outcomes. Excessive …

Preterm birth (PTB) is a leading cause of neonatal morbidity and mortality worldwide, yet the
cellular and molecular mechanisms driving this condition remain undeciphered, thus limiting …

Preeclampsia (PE) is a disorder of pregnancy that manifests as late gestational maternal
hypertension and proteinuria and can be life-threatening to both the mother and baby. It is …