Advancement in exosome isolation and label-free detection towards clinical diagnosis

Y Zhou, H Liu, H Chen - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Studies have demonstrated the promise of exosomes as diagnostic biomarkers and
therapeutic targets for disease diagnosis, treatment, and prognostic assessment. To facilitate …

A Panorama of Extracellular Vesicle Applications: From Biomarker Detection to Therapeutics

S Das, CJ Lyon, T Hu - ACS nano, 2024 - ACS Publications
Extracellular vesicles (EVs) secreted by all cell types are involved in the cell-to-cell transfer
of regulatory factors that influence cell and tissue phenotypes in normal and diseased …

An updated review on the development of a nanomaterial-based field-effect transistor-type biosensors to detect exosomes for cancer diagnosis

J An, H Park, M Ju, Y Woo, Y Seo, J Min, T Lee - Talanta, 2024 - Elsevier
Cancer, a life-threatening genetic disease caused by abnormalities in normal cell growth
regulatory functions, poses a significant challenge that current medical technologies cannot …

Composition, functions, and applications of exosomal membrane proteins

F Xu, S Luo, P Lu, C Cai, W Li, C Li - Frontiers in Immunology, 2024 - frontiersin.org
Exosomes play a crucial role in various biological processes, such as human development,
immune responses, and disease occurrence. The membrane proteins on exosomes are …

[HTML][HTML] Simultaneous detection of membrane protein and mRNA at single extracellular vesicle level by droplet microfluidics for cancer diagnosis

H Lin, B Li, J Guo, X Mai, H Yu, W Pan, B Wu… - Journal of Advanced …, 2024 - Elsevier
Introduction Simultaneous detection of proteins and mRNA within a single extracellular
vesicle (EV) enables comprehensive analysis of specific EVs subpopulations, significantly …

Integrated FET sensing microsystem for specific detection of pancreatic cancer exosomal miRNA10b

Y Yu, C Liang, QQ Wan, D **, X Liu, Z Zhang… - Analytica Chimica …, 2023 - Elsevier
Tumor-derived exosome (TD-Ex) serves as a crucial early diagnostic biomarker of
pancreatic cancer (PC). However, accurate identification of TD-Ex from PC is still a …

Accurate diagnosis of thyroid cancer using a combination of surface-enhanced Raman spectroscopy of exosome on MXene-coated gold@ silver core@ shell …

X Sun, B Chen, Z Li, Y Shan, M Jian, X Meng… - Chemical Engineering …, 2024 - Elsevier
Exosomes (EVs), serving as one of the optimal subjects for liquid biopsies, have seen broad
applications in diagnosing various diseases, including cancers. In this paper, an efficient …