Insights into the kinetics of Ca2+-regulated contraction and relaxation from myofibril studies

R Stehle, J Solzin, B Iorga, C Poggesi - Pflügers Archiv-European Journal …, 2009 - Springer
Muscle contraction results from force-generating interactions between myosin cross-bridges
on the thick filament and actin on the thin filament. The force-generating interactions are …

Contractile system of muscle as an auto-oscillator

S Ishiwata, Y Shimamoto, N Fukuda - Progress in Biophysics and Molecular …, 2011 - Elsevier
It is widely known that the contractile system of muscle takes on either the state of
contraction (force-generating) or the state of relaxation (non-force-generating), which is …

Real-time monitoring of cell elasticity reveals oscillating myosin activity

H Schillers, M Wälte, K Urbanova, H Oberleithner - Biophysical journal, 2010 - cell.com
The cytoskeleton is the physical and biochemical interface for a large variety of cellular
processes. Its complex regulation machinery is involved upstream and downstream in …

Direct observation of the myosin-Va power stroke and its reversal

JR Sellers, C Veigel - Nature structural & molecular biology, 2010 - nature.com
Complex forms of cellular motility, including cell division, organelle trafficking or signal
amplification in the auditory system, require strong coordination of the myosin motors …

Force produced by isolated sarcomeres and half-sarcomeres after an imposed stretch

DE Rassier, I Pavlov - American Journal of Physiology-Cell …, 2012 - journals.physiology.org
When a stretch is imposed to activated muscles, there is a residual force enhancement that
persists after the stretch; the force is higher than that produced during an isometric …

Dynamical behavior of molecular motor assemblies in the rigid and crossbridge models

T Guérin, J Prost, JF Joanny - The European Physical Journal E, 2011 - Springer
We present a detailed analysis of the dynamical instabilities appearing in two kinetic
theories for the collective behavior of molecular motors: the rigid two-state model and the …

Inter-sarcomere coordination in muscle revealed through individual sarcomere response to quick stretch

Y Shimamoto, M Suzuki, SV Mikhailenko… - Proceedings of the …, 2009 - pnas.org
The force generation and motion of muscle are produced by the collective work of thousands
of sarcomeres, the basic structural units of striated muscle. Based on their series connection …

Nanoscopic changes in the lattice structure of striated muscle sarcomeres involved in the mechanism of spontaneous oscillatory contraction (SPOC)

F Kono, S Kawai, Y Shimamoto, S Ishiwata - Scientific reports, 2020 - nature.com
Muscles perform a wide range of motile functions in animals. Among various types are
skeletal and cardiac muscles, which exhibit a steady auto-oscillation of force and length …

Properties of extensor digitorum longus muscle and skinned fibers from adult and aged male and female Actn3 knockout mice

S Chan, JT Seto, PJ Houweling, N Yang… - Muscle & …, 2011 - Wiley Online Library
Abstract Absence of α‐actinin‐3, encoded by the ACTN3 “speed gene,” is associated with
poorer sprinting performance in athletes and a slowing of relaxation in fast‐twitch muscles of …

Residual force enhancement in skeletal muscles: one sarcomere after the other

DE Rassier - Journal of muscle research and cell motility, 2012 - Springer
The force–length relation is one of the most prominent features of striated muscles, and
predicts that the force produced by a fully activated muscle is proportional to the overlap …