Glucose is the long-established, obligatory fuel for brain that fulfills many critical functions,
including ATP production, oxidative stress management, and synthesis of neurotransmitters …

Metabolism is an essential part of life that provides energy for cell growth. During metabolic
flux, reactive electrophiles are produced that covalently modify macromolecules, leading to …

Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …

Glycation is both a physiological and pathological process which mainly affects proteins,
nucleic acids and lipids. Exogenous and endogenous glycation produces deleterious …

The brain is a highly metabolically active organ requiring a large amount of glucose.
Methylglyoxal (MGO), a by-product of glucose metabolism, is known to be involved in …

It appears that electronic cigarettes (EC) are a less harmful alternative to conventional
cigarette (CC) smoking, as they generate substantially lower levels of harmful carcinogens …

The looming severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a
long-lasting pandemic of coronavirus disease 2019 (COVID-19) around the globe with …

The sigma 2 receptor (σ2R) was described pharmacologically more than three decades ago,
but its molecular identity remained obscure until recently when it was identified as …

As of late, evidence has been emerging that the Maillard reaction (MR, also referred to as
glycation) affects the structure and function of food proteins. MR induces the conformational …

Abstract Aims Advanced glycation endproducts (AGEs) are sugar-modified adducts which
arise during non-enzymatic glycoxidative stress. These compounds may become …