Cardiac biomarkers of acute coronary syndrome: from history to high-sensitivity cardiac troponin

P Garg, P Morris, AL Fazlanie, S Vijayan… - Internal and emergency …, 2017 - Springer
The role of cardiac troponins as diagnostic biomarkers of myocardial injury in the context of
acute coronary syndrome (ACS) is well established. Since the initial 1st-generation assays …

Cardiac troponin level elevations not related to acute coronary syndromes

E Giannitsis, HA Katus - Nature reviews cardiology, 2013 - nature.com
Over the past 2 decades, cardiac troponins (cTn) have emerged as the preferred biomarkers
for the noninvasive detection of myocardial injury. In conjunction with typical clinical findings …

Prognostic value of cardiac troponin I measured with a highly sensitive assay in patients with stable coronary artery disease

T Omland, MA Pfeffer, SD Solomon… - Journal of the American …, 2013 - jacc.org
Objectives: The aims of this study were to assess the prognostic value of cardiac troponin I
levels, measured with a new high-sensitivity assay, in low-risk patients with stable coronary …

Clearance of cardiac troponin T with and without kidney function

V Fridén, K Starnberg, A Muslimovic, SE Ricksten… - Clinical …, 2017 - Elsevier
Objective The extent of kidney-dependent clearance of the cardiac damage biomarker
cardiac troponin T (cTnT) is not known. Methods and results We examined clearance of …

Clinical benefit of high-sensitivity cardiac troponin I in the detection of exercise-induced myocardial ischemia

G Lee, R Twerenbold, Y Tanglay, T Reichlin… - American heart …, 2016 - Elsevier
Background A pilot study using a novel high-sensitivity cardiac troponin I (hs-cTnI) assay
suggested that cTnI might be released into blood during exercise-induced myocardial …

Severity of obstructive sleep apnea is associated with cardiac troponin I concentrations in a community-based sample: data from the Akershus Sleep Apnea Project

G Einvik, H Røsjø, A Randby, SK Namtvedt… - Sleep, 2014 - academic.oup.com
Objectives: Previous community-based studies have failed to demonstrate an independent
association between OSA and circulating cardiac troponin concentrations, a marker of …

Prospective validation of a biomarker-based rule out strategy for functionally relevant coronary artery disease

JE Walter, U Honegger, C Puelacher… - Clinical …, 2018 - academic.oup.com
BACKGROUND This study aimed to prospectively advance a rule-out strategy for
functionally significant coronary artery disease (CAD) by use of high-sensitivity cardiac …

Troponin I measured by a high-sensitivity assay in patients with suspected reversible myocardial ischemia: data from the Akershus Cardiac Examination (ACE) 1 study

H Røsjø, G Kravdal, AD Høiseth, M Jørgensen… - Clinical …, 2012 - academic.oup.com
BACKGROUND Whether cardiac troponin concentrations are increased by reversible
myocardial ischemia is controversial. Differences in the structure of cardiac troponin I (cTnI) …

Cardiovascular risk of veterans' football: An observational cohort study with follow-up

F Egger, T Schilling, S Baumann, T Meyer, J Scharhag - Plos one, 2024 - journals.plos.org
Background The cardiac stress for veteran football players during match is considerable. In
this specific elderly population, the kinetics of exercise-induced cardiac troponin I (cTnI) and …

Troponins in heart failure

T Omland, H Røsjø, E Giannitsis, S Agewall - Clinica chimica acta, 2015 - Elsevier
The signs and symptoms of heart failure are frequently unspecific and correlate poorly with
objective indices of cardiac function. Objective assessment of cardiac function by …