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[HTML][HTML] A historical review of brain drug delivery
WM Pardridge - Pharmaceutics, 2022 - mdpi.com
The history of brain drug delivery is reviewed beginning with the first demonstration, in 1914,
that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood …
that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood …
Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs
M Agrawal, S Saraf, S Saraf, SG Antimisiaris… - Journal of controlled …, 2018 - Elsevier
Abstract According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …
Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems
M Karimi, A Ghasemi, PS Zangabad… - Chemical Society …, 2016 - pubs.rsc.org
New achievements in the realm of nanoscience and innovative techniques of nanomedicine
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …
Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come
P Yingchoncharoen, DS Kalinowski… - Pharmacological …, 2016 - Elsevier
Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …
Structure-function and application of plant lectins in disease biology and immunity
Lectins are proteins with a high degree of stereospecificity to recognize various sugar
structures and form reversible linkages upon interaction with glyco-conjugate complexes …
structures and form reversible linkages upon interaction with glyco-conjugate complexes …
PEGylation for enhancing nanoparticle diffusion in mucus
JT Huckaby, SK Lai - Advanced drug delivery reviews, 2018 - Elsevier
The viscoelastic mucus secretions coating exposed organs such as the lung airways and the
female reproductive tract can trap and quickly eliminate not only foreign pathogens and …
female reproductive tract can trap and quickly eliminate not only foreign pathogens and …
Basics and recent advances in peptide and protein drug delivery
BJ Bruno, GD Miller, CS Lim - Therapeutic delivery, 2013 - Taylor & Francis
While the peptide and protein therapeutic market has developed significantly in the past
decades, delivery has limited their use. Although oral delivery is preferred, most are …
decades, delivery has limited their use. Although oral delivery is preferred, most are …
Temperature-responsive smart nanocarriers for delivery of therapeutic agents: applications and recent advances
M Karimi, P Sahandi Zangabad… - … applied materials & …, 2016 - ACS Publications
Smart drug delivery systems (DDSs) have attracted the attention of many scientists, as
carriers that can be stimulated by changes in environmental parameters such as …
carriers that can be stimulated by changes in environmental parameters such as …
Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery
J Nicolas, S Mura, D Brambilla, N Mackiewicz… - Chemical Society …, 2013 - pubs.rsc.org
Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …
Surface-modified nanocarriers for nose-to-brain delivery: from bioadhesion to targeting
In the field of nasal drug delivery, nose-to-brain delivery is among the most fascinating
applications, directly targeting the central nervous system, bypassing the blood brain barrier …
applications, directly targeting the central nervous system, bypassing the blood brain barrier …