Lanthanide complexes as chiral probes exploiting circularly polarized luminescence

R Carr, NH Evans, D Parker - Chemical Society Reviews, 2012 - pubs.rsc.org
Optical probes that provide information about local chirality have been developed based on
changes to the circular polarisation of emitted light. Highly emissive complexes of lanthanide …

Lanthanide circularly polarized luminescence: bases and applications

F Zinna, L Di Bari - Chirality, 2015 - Wiley Online Library
Lanthanide (III) luminescence is very characteristic: it is characterized by narrow emission
bands, large Stokes shift, and a long excited state lifetime. Moreover, chiral lanthanide …

EuroTracker® dyes: design, synthesis, structure and photophysical properties of very bright europium complexes and their use in bioassays and cellular optical …

SJ Butler, M Delbianco, L Lamarque… - Dalton …, 2015 - pubs.rsc.org
The development of the brightest luminescent europium (III) complexes is traced, including
analysis of the C3-symmetric core complex based on a functionalized triazacyclononane …

Chiral probes for α 1-AGP reporting by species-specific induced circularly polarised luminescence

S Shuvaev, EA Suturina, K Mason, D Parker - Chemical Science, 2018 - pubs.rsc.org
Luminescence spectroscopy has been used to monitor the selective and reversible binding
of pH sensitive, macrocyclic lanthanide complexes,[LnL1], to the serum protein α1-AGP …

Circularly Polarised Luminescence from Helically Chiral “Confused” N,N,O,C‐Boron‐Chelated Dipyrromethenes (BODIPYs)

R Clarke, KL Ho, AA Alsimaree, OJ Woodford… - …, 2017 - Wiley Online Library
Chiral organic fluorophores have significant promise in the development of efficient emitters
of circularly polarized light. Herein we describe a helically chiral boron dipyrromethene …

Enantioselective cellular localisation of europium (III) coordination complexes

AT Frawley, HV Linford, M Starck, R Pal, D Parker - Chemical Science, 2018 - pubs.rsc.org
The selective mitochondrial localisation of the Λ enantiomer of three different emissive
europium (III) complexes in NIH 3T3 and MCF7 cells contrasts with the behaviour of the Δ …

Molecular dynamics approach to probe the allosteric inhibition of PTP1B by chlorogenic and cichoric acid

SK Baskaran, N Goswami, S Selvaraj… - Journal of chemical …, 2012 - ACS Publications
Protein tyrosine phosphatase 1B (PTP1B), a major negative regulator of the insulin and
leptin signaling pathway, is a potential target for therapeutic intervention against diabetes …

Anisotropic 1H STD‐NMR Spectroscopy: Exploration of Enantiomer‐Polypeptide Interactions in Chiral Oriented Environments

B Gouilleux, FM Moussallieh, P Lesot - ChemPhysChem, 2023 - Wiley Online Library
We explore and report for the first time the use of 1H saturation transfer difference NMR
experiments (STD‐NMR) in weakly aligning chiral anisotropic media to identify the hydrogen …

A chiral probe for the acute phase proteins alpha-1-acid glycoprotein and alpha-1-antitrypsin based on europium luminescence

R Carr, L Di Bari, SL Piano, D Parker… - Dalton …, 2012 - pubs.rsc.org
Reversible and selective binding of a dynamically racemic europium (III) complex to α1-acid
glycoprotein and α1-antitrypsin is characterised by a significant change in the europium total …

Interaction of lafutidine in binding to human serum albumin in gastric ulcer therapy: STD-NMR, WaterLOGSY-NMR, NMR relaxation times, Tr-NOESY, molecule …

H Yang, Y Huang, J He, S Li, B Tang, H Li - Archives of biochemistry and …, 2016 - Elsevier
In this study, lafutidine (LAF) was used as a model compound to investigate the binding
mechanism between antiulcer drugs and human serum albumin (HSA) through various …