The potential of oligonucleotide therapeutics is undeniable as more than 15 drugs have
been approved to treat various diseases in the liver, central nervous system (CNS), and …

Self-assembled nanostructures that are sensitive to environmental stimuli are promising
nanomaterials for drug delivery. In this class, disulfide-containing redox-sensitive strategies …

Peptide-based neoantigen vaccines hold tremendous potential for personalized tumor
immunotherapy. However, effective delivery and controllable release of antigen peptides …

Ultrasmall nanoparticles (USNs)(nanoparticles with hydrodynamic diameter< 10 nm) are
being widely developed pre‐clinically and started to emerge in clinical trials over the last …

Disulfide conjugation invariably remains a key tool in research on nucleic acids. This
versatile and cost-effective method plays a crucial role in structural studies of DNA and RNA …

Peptide and protein bioconjugation sees ever‐growing applications in the pharmaceutical
sector. Novel strategies and reagents that can address the chemo‐and regioselectivity …

The comprehensive advancement in DNA modification and coupling is driving DNA
nanotechnology to new heights, paving the way for groundbreaking innovations in …

The low-bias current–voltage technique was utilized to study charge transport in single-
stranded DNA (ssDNA), assessing the method's effectiveness for future studies aimed at …

Co-delivery systems of siRNA and chemotherapeutic drugs have been developed as an
attractive strategy to optimize the efficacy of chemotherapy towards cancer cells with …

The synthesis and incorporation of a tosylated phosphoramidite linker containing a disulfide
bond is described. Incorporation of the linker into short DNA and RNA oligomers proceeded …