Role of CaMKII in diabetes induced vascular injury and its interaction with anti-diabetes therapy

S Chacar, A Abdi, K Almansoori, J Alshamsi… - Reviews in Endocrine …, 2024 - Springer
Diabetes mellitus is a metabolic disorder denoted by chronic hyperglycemia that drives
maladaptive structural changes and functional damage to the vasculature. Attenuation of this …

High-intensity interval training ameliorates molecular changes in the hippocampus of male rats with the diabetic brain: the role of adiponectin

K Khoramipour, MA Bejeshk, MA Rajizadeh… - Molecular …, 2023 - Springer
Alzheimer's disease (AD) is closely related to type 2 diabetes (T2D). This study investigated
the impact of high-intensity interval training (HIIT) on diabetes-induced disturbances in AD …

Lactate-induced autophagy activation: unraveling the therapeutic impact of high-intensity interval training on insulin resistance in type 2 diabetic rats

H Pirani, A Soltany, M Hossein Rezaei… - Scientific Reports, 2024 - nature.com
Impaired autophagy is a hallmark of diabetes. The current study proposed to investigate if
high intensity interval training (HIIT) induced lactate accumulation could stimulate autophagy …

[HTML][HTML] High-intensity interval training reduced oxidative stress and apoptosis in the hippocampus of male rats with type 2 diabetes: The role of the PGC1α-Keap1 …

N Ebrahimnezhad, S Nayebifar, Z Soltani… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Objective (s): This study aimed to determine the effect of 8-week high-intensity interval
training (HIIT) on oxidative stress and apoptosis in the hippocampus of male rats with type 2 …

Exercise training improves diabetic renal injury by reducing fetuin-A, oxidative stress and inflammation in type 2 diabetic rats

S Saberi, M Askaripour, M Khaksari, MA Rajizadeh… - Heliyon, 2024 - cell.com
Background Diabetic kidney disease (DKD) stands as a primary contributor to end-stage
renal disease, associated with heightened mortality in cardiovascular diseases. This study …

ATP releasing channels and the ameliorative effects of high intensity interval training on diabetic heart: a multifaceted analysis

S Joukar, MA Rajizadeh, MA Bejeshk, SS Alavi… - Scientific Reports, 2024 - nature.com
Abstract Type 2 diabetes (T2D) can cause severe cardiac complications at functional,
histologic and molecular levels. These pathological complications could be mediated by …

The effects of eight weeks of circuit resistance training on serum METRNL levels and insulin resistance in individuals with type 2 diabetes

SM Tayebi, M Golmohammadi, R Eslami… - Journal of Diabetes & …, 2023 - Springer
Purpose The effects of exercise training on meteorin-like protein (METRNL), one of the
newest factors involved, is one of the treatment strategies for diabetes. The present study …

Interactions between the ERK1/2 signaling pathway and PCAF play a key role in PE‑induced cardiomyocyte hypertrophy

Q Mao, S Wu, C Peng, B Peng… - Molecular …, 2021 - spandidos-publications.com
Cardiomyocyte hypertrophy is a compensatory phase of chronic heart failure that is induced
by the activation of multiple signaling pathways. The extracellular signal‑regulated protein …

Changes in the hippocampal level of tau but not beta-amyloid may mediate anxiety-like behavior improvement ensuing from exercise in diabetic female rats

K Khoramipour, MH Rezaei, A Moslemizadeh… - Behavioral and Brain …, 2024 - Springer
Background In the present study, we investigated the effect of high-intensity interval training
(HIIT) on cognitive behaviors in female rats with a high-fat diet+ streptozotocin (STZ) …

The effect of 12 weeks of aerobic exercise training with or without saffron supplementation on diabetes‐specific markers and inflammation in women with type 2 …

A Rajabi, A Akbar Nezhad Gharehlo… - European Journal of …, 2024 - Wiley Online Library
This study was conducted to investigate the effects of 12 weeks of aerobic exercise (AT) and
saffron supplementation on hemostasis, inflammatory markers, and insulin resistance in …