The multifaceted biology of plasmacytoid dendritic cells
M Swiecki, M Colonna - Nature Reviews Immunology, 2015 - nature.com
Plasmacytoid dendritic cells (pDCs) are a unique DC subset that specializes in the
production of type I interferons (IFNs). pDCs promote antiviral immune responses and have …
production of type I interferons (IFNs). pDCs promote antiviral immune responses and have …
Biological role of granulocyte macrophage colony-stimulating factor (GM-CSF) and macrophage colony-stimulating factor (M-CSF) on cells of the myeloid lineage
I Ushach, A Zlotnik - Journal of Leucocyte Biology, 2016 - academic.oup.com
Abstract M-CSF and GM-CSF are 2 important cytokines that regulate macrophage numbers
and function. Here, we review their known effects on cells of the macrophage-monocyte …
and function. Here, we review their known effects on cells of the macrophage-monocyte …
Inflammatory and immune pathways in the pathogenesis of periodontal disease
The pathogenesis of periodontitis involves a complex immune/inflammatory cascade that is
initiated by the bacteria of the oral biofilm that forms naturally on the teeth. The susceptibility …
initiated by the bacteria of the oral biofilm that forms naturally on the teeth. The susceptibility …
CSF-1 receptor signaling in myeloid cells
The CSF-1 receptor (CSF-1R) is activated by the homodimeric growth factors colony-
stimulating factor-1 (CSF-1) and interleukin-34 (IL-34). It plays important roles in …
stimulating factor-1 (CSF-1) and interleukin-34 (IL-34). It plays important roles in …
[HTML][HTML] Targeting CSF-1R represents an effective strategy in modulating inflammatory diseases
C **ang, H Li, W Tang - Pharmacological Research, 2023 - Elsevier
Abstract Colony-stimulating factor-1 receptor (CSF-1R), also known as FMS kinase, is a type
I single transmembrane protein mainly expressed in myeloid cells, such as monocytes …
I single transmembrane protein mainly expressed in myeloid cells, such as monocytes …
Deciphering the transcriptional network of the dendritic cell lineage
Although much progress has been made in the understanding of the ontogeny and function
of dendritic cells (DCs), the transcriptional regulation of the lineage commitment and …
of dendritic cells (DCs), the transcriptional regulation of the lineage commitment and …
Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling
Macrophage-colony stimulating factor (CSF-1) signaling through its receptor (CSF-1R)
promotes the differentiation of myeloid progenitors into heterogeneous populations of …
promotes the differentiation of myeloid progenitors into heterogeneous populations of …
Blood monocytes: development, heterogeneity, and relationship with dendritic cells
C Auffray, MH Sieweke… - Annual review of …, 2009 - annualreviews.org
Monocytes are circulating blood leukocytes that play important roles in the inflammatory
response, which is essential for the innate response to pathogens. But inflammation and …
response, which is essential for the innate response to pathogens. But inflammation and …
[HTML][HTML] Development of conventional dendritic cells: from common bone marrow progenitors to multiple subsets in peripheral tissues
Our understanding of conventional dendritic cell (cDC) development and the functional
specializations of distinct subsets in the peripheral tissues has increased greatly in recent …
specializations of distinct subsets in the peripheral tissues has increased greatly in recent …
[HTML][HTML] Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossification
LJ Raggatt, ME Wullschleger, KA Alexander… - The American journal of …, 2014 - Elsevier
The distribution, phenotype, and requirement of macrophages for fracture-associated
inflammation and/or early anabolic progression during endochondral callus formation were …
inflammation and/or early anabolic progression during endochondral callus formation were …