N-Oxides of heterocyclic compounds are the focus of medical chemistry due to their diverse
biological properties. The high reactivity and tendency to undergo various rearrangements …

Despite recent advances in the treatment of colorectal cancer (CRC), low patient survival
rate due to emergence of drug resistant cancer cells, metastasis and multiple deleterious …

In the quest for rare earth metal complexes with enhanced cancer chemotherapeutic
properties, the discovery of seven lanthanide (III) complexes bearing 8-hydroxyquinoline-N …

Approximately 90% of cancer-associated deaths result from disseminated tumors, indicating
the ineffectiveness of current therapies and the imperative need of antimetastatic drugs. A …

With the aim of shedding some light on the mechanism of action of zinc (II) complexes in
antiproliferative processes and molecular signaling pathways, three novel glycosylated zinc …

Three new cobalt (II) complexes,[Co (MQL) 2Cl2](CoCl),[Co (MQL) 2Br2](CoBr), and [Co
(MQL) 2I2](CoI), bearing 8-methoxyquinoline (MQL) have been designed for the first time …

Hetero mononuclear rhenium (I) complexes (IV) using ligands (L 1-L 5)[L 1-L 5= 11-((2-
chlorobenzylidene) hydrazono)-11H-indeno [1, 2-b] quinoxaline (L 1), 8-methyl-11-((4 …

Mitophagy, a selective autophagic process, has emerged as a pathway involved in
degrading dysfunctional mitochondria. Herein, new platinum (II)-based chemotherapeutics …

Natural compounds, such as paclitaxel and camptothecin, have great effects on the
treatment of tumors. Such natural chemicals often achieve anti-tumor effects through a …

Peptide-based drugs are gaining significant momentum in the modern drug discovery, which
is witnessed by the approval of new drugs by the FDA in recent years. On the other hand …