Detecting attractors in biological models with uncertain parameters
Complex behaviour arising in biological systems is typically characterised by various kinds
of attractors. An important problem in this area is to determine these attractors. Biological …
of attractors. An important problem in this area is to determine these attractors. Biological …
Computational Modelling of Metabolic Burden and Substrate Toxicity in Escherichia coli Carrying a Synthetic Metabolic Pathway
In our previous work, we designed and implemented a synthetic metabolic pathway for 1, 2,
3-trichloropropane (TCP) biodegradation in Escherichia coli. Significant effects of metabolic …
3-trichloropropane (TCP) biodegradation in Escherichia coli. Significant effects of metabolic …
Pithya: a parallel tool for parameter synthesis of piecewise multi-affine dynamical systems
We present a novel tool for parameter synthesis of piecewise multi-affine dynamical systems
from specifications expressed in a hybrid branching-time temporal logic. The tool is based …
from specifications expressed in a hybrid branching-time temporal logic. The tool is based …
Fully automated attractor analysis of cyanobacteria models
Complex dynamics arising in biological systems can be characterised by various kinds of
attractors. To that end, the task of determining attractors becomes important in modern …
attractors. To that end, the task of determining attractors becomes important in modern …
Parallel Parameter Synthesis for Multi-affine Hybrid Systems from Hybrid CTL Specifications
E Šmijáková, S Pastva, D Šafránek, L Brim - Computational Methods in …, 2020 - Springer
We consider the parameter synthesis problem for multi-affine hybrid systems and properties
specified using a hybrid extension of CTL (HCTL). The goal is to determine the sets of …
specified using a hybrid extension of CTL (HCTL). The goal is to determine the sets of …
[PDF][PDF] Discrete Bifurcation Analysis
S Pastva, RNDL BRIM - 2019 - is.muni.cz
When trying to describe and understand real-world phenomena, science often relies on a
model-based approach, where the true nature of the system is described in some simplified …
model-based approach, where the true nature of the system is described in some simplified …
[PDF][PDF] Formal methods for model selection in systems biology
M Hajnal - Master's thesis, Masaryk University, Brno, Czech …, 2018 - is.muni.cz
We address the problem of selecting model from candidate list in the field of systems
biology. The selection is based on model behaviour specified in temporal logic rather than …
biology. The selection is based on model behaviour specified in temporal logic rather than …
[PDF][PDF] Discrete Bifurcation Analysis
M Samuel, RND Luboš - is.muni.cz
When trying to describe and understand real-world phenomena, science often relies on a
model-based approach, where the true nature of the system is described in some simplified …
model-based approach, where the true nature of the system is described in some simplified …
The modelling and synthesis of chemical reaction networks
M Whitby - 2020 - ora.ox.ac.uk
Biochemical systems have been influenced, altered, and engineered to produce a myriad of
complex behaviours that have far reaching consequences in the realization of computational …
complex behaviours that have far reaching consequences in the realization of computational …
Multi-approaches to achieve an advanced cognitive agent in a new type of parallel processing computer
X Yuan - 2020 - hekyll.services.adelaide.edu.au
In this work, we addressed the problem of develo** an agent-based artificial general
intelligence that can be implemented in compact and power-efficient electronic hardware …
intelligence that can be implemented in compact and power-efficient electronic hardware …