Intravitreal administration is the method of choice in drug delivery to the retina and/or
choroid. Rabbit is the most commonly used animal species in intravitreal pharmacokinetics …

Abstract Treatment and management of diseases of the posterior segment of the eye such
as diabetic retinopathy, retinoblastoma, retinitis pigmentosa, and choroidal …

Although once daily anti-glaucoma drug therapy is a current clinical reality, most therapies
require multiple dosing and there is an unmet need to develop convenient, safe, and …

Topical ocular drug bioavailability is notoriously poor, in the order of 5% or less. This is a
consequence of effective multiple barriers to drug entry, comprising nasolacrimal drainage …

Periocular administration is a potential way of delivering drugs to their targets in posterior
eye segment (vitreous, neural retina, retinal pigment epithelium (RPE), choroid). Purpose of …

The release of drug from bacterial cellulose (BC) is tuned to achieve immediate and
controlled delivery by using two drying strategies: freeze-drying and oven-drying. Diclofenac …

Novel poly (ethylene oxide)(PEO) hydrogel films were synthesized via UV cross-linking with
pentaerythritol tetra-acrylate (PETRA) as cross-linking agent. The purpose of this work was …

The transdermal application of actives offers numerous advantages over other conventional
routes. Namely, a stable level of drugs in the bloodstream and reduced side effects are the …

Although the eye is an accessible organ for direct drug application, ocular drug delivery
remains a major challenge due to multiple barriers within the eye. Key barriers include static …

The aim of the present work was to investigate the role of montmorillonite clay as an oral
drug delivery carrier for in vitro controlled release of anti-inflammatory drug diclofenac …