The origin and pathogenesis of endometriosis
Recent molecular genetic findings on endometriosis and normal endometrium suggest a
modified model in which circulating epithelial progenitor or stem cells intended to …
modified model in which circulating epithelial progenitor or stem cells intended to …
Proteoglycan chemical diversity drives multifunctional cell regulation and therapeutics
The extracellular matrix (ECM) constitutes a highly dynamic three-dimensional structural
network comprised of macromolecules, such as proteoglycans/glycosaminoglycans …
network comprised of macromolecules, such as proteoglycans/glycosaminoglycans …
New concepts in cancer biomarkers: circulating miRNAs in liquid biopsies
The effective and efficient management of cancer patients relies upon early diagnosis and/or
the monitoring of treatment, something that is often difficult to achieve using standard tissue …
the monitoring of treatment, something that is often difficult to achieve using standard tissue …
Syndecan-1 is a novel molecular marker for triple negative inflammatory breast cancer and modulates the cancer stem cell phenotype via the IL-6/STAT3, Notch and …
Background Inflammatory breast cancer (IBC), a particularly aggressive form of breast
cancer, is characterized by cancer stem cell (CSC) phenotype. Due to a lack of targeted …
cancer, is characterized by cancer stem cell (CSC) phenotype. Due to a lack of targeted …
Proteoglycans remodeling in cancer: Underlying molecular mechanisms
Extracellular matrix is a highly dynamic macromolecular network. Proteoglycans are major
components of extracellular matrix playing key roles in its structural organization and cell …
components of extracellular matrix playing key roles in its structural organization and cell …
Cell-surface heparan sulfate proteoglycans as multifunctional integrators of signaling in cancer
Proteoglycans (PGs) represent a large proportion of the components that constitute the
extracellular matrix (ECM). They are a diverse group of glycoproteins characterized by a …
extracellular matrix (ECM). They are a diverse group of glycoproteins characterized by a …
An integrated electrochemical nanodevice for intracellular RNA collection and detection in single living cell
HY Wang, YF Ruan, LB Zhu, XM Shi… - Angewandte …, 2021 - Wiley Online Library
New tools for single‐cell interrogation enable deeper understanding of cellular
heterogeneity and associated cellular behaviors and functions. Information of RNA …
heterogeneity and associated cellular behaviors and functions. Information of RNA …
[HTML][HTML] Cross-talk between estradiol receptor and EGFR/IGF-IR signaling pathways in estrogen-responsive breast cancers: focus on the role and impact of …
In hormone-dependent breast cancer, estrogen receptors are the principal signaling
molecules that regulate several cell functions either by the genomic pathway acting directly …
molecules that regulate several cell functions either by the genomic pathway acting directly …
Roles of non-coding RNAs and angiogenesis in glioblastoma
E Balandeh, K Mohammadshafie… - Frontiers in cell and …, 2021 - frontiersin.org
One of the significant hallmarks of cancer is angiogenesis. It has a crucial function in tumor
development and metastasis. Thus, angiogenesis has become one of the most exciting …
development and metastasis. Thus, angiogenesis has become one of the most exciting …
DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer
Z Li, H Lei, M Luo, Y Wang, L Dong, Y Ma, C Liu… - Gastric cancer, 2015 - Springer
Background MicroRNAs act as tumor suppressors or oncogenes. The pathological roles of
miRNAs in gastric tumorigenesis are largely unknown. Although miR-10b was identified as …
miRNAs in gastric tumorigenesis are largely unknown. Although miR-10b was identified as …