Targeting epithelial–mesenchymal transition (EMT) to overcome drug resistance in cancer
Epithelial–mesenchymal transition (EMT) is known to play an important role in cancer
progression, metastasis and drug resistance. Although there are controversies surrounding …
progression, metastasis and drug resistance. Although there are controversies surrounding …
Regulation of the master regulator FOXM1 in cancer
GB Liao, XZ Li, S Zeng, C Liu, SM Yang, L Yang… - Cell Communication and …, 2018 - Springer
FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor
that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the …
that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the …
FOXM1 and cancer: faulty cellular signaling derails homeostasis
Forkhead box transcription factor, FOXM1 is implicated in several cellular processes such as
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …
Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes
Background MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In
this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients …
this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients …
Hypoxia-induced TUFT1 promotes the growth and metastasis of hepatocellular carcinoma by activating the Ca2+/PI3K/AKT pathway
C Dou, Z Zhou, Q Xu, Z Liu, Y Zeng, Y Wang, Q Li… - Oncogene, 2019 - nature.com
Abstract Tuftelin1 (TUFT1), an acidic protein constituent of develo** and mineralizing
tooth tissues, is regulated by hypoxia and the Hedgehog signaling pathway. We investigated …
tooth tissues, is regulated by hypoxia and the Hedgehog signaling pathway. We investigated …
HNRNPA2/B1 is upregulated in endocrine-resistant LCC9 breast cancer cells and alters the miRNA transcriptome when overexpressed in MCF-7 cells
MicroRNAs are dysregulated in breast cancer. Heterogeneous Nuclear Ribonucleoprotein
A2/B1 (HNRNPA2/B1) is a reader of the N (6)-methyladenosine (m6A) mark in primary …
A2/B1 (HNRNPA2/B1) is a reader of the N (6)-methyladenosine (m6A) mark in primary …
RETRACTED: Circular RNA circ_0001946 acts as a competing endogenous RNA to inhibit glioblastoma progression by modulating miR‐671‐5p and CDR1
X Li, H Diao - Journal of cellular physiology, 2019 - Wiley Online Library
Objectives In many malignant tumors, circRNAs play an important role. However, the
biological role and clinical significance of circRNAs remain unclear. In this study, we …
biological role and clinical significance of circRNAs remain unclear. In this study, we …
Identification of plasma microRNA expression changes in multiple system atrophy and Parkinson's disease
H Uwatoko, Y Hama, IT Iwata, S Shirai, M Matsushima… - Molecular Brain, 2019 - Springer
MicroRNAs (miRNAs) are endogenous small (18–25 nt), single-stranded, non-coding RNAs
that play key roles in post-transcriptional gene expression regulation. The expression …
that play key roles in post-transcriptional gene expression regulation. The expression …
LncRNA UCA1-miR-507-FOXM1 axis is involved in cell proliferation, invasion and G0/G1 cell cycle arrest in melanoma
Y Wei, Q Sun, L Zhao, J Wu, X Chen, Y Wang, W Zang… - Medical Oncology, 2016 - Springer
Recently, the incidence of melanoma has been on the rise. Patients with distant metastasis
share poor prognosis. Increasing studies have been conducted to clarify the molecular …
share poor prognosis. Increasing studies have been conducted to clarify the molecular …
MicroRNAs association with azoospermia, oligospermia, asthenozoospermia, and teratozoospermia: a systematic review
Infertility is a major health problem across the world. One of the main reasons for male
infertility are defects in sperm. Semen analysis is the most common test utilized to evaluate …
infertility are defects in sperm. Semen analysis is the most common test utilized to evaluate …