Targeting epithelial–mesenchymal transition (EMT) to overcome drug resistance in cancer

B Du, JS Shim - Molecules, 2016 - mdpi.com
Epithelial–mesenchymal transition (EMT) is known to play an important role in cancer
progression, metastasis and drug resistance. Although there are controversies surrounding …

Regulation of the master regulator FOXM1 in cancer

GB Liao, XZ Li, S Zeng, C Liu, SM Yang, L Yang… - Cell Communication and …, 2018 - Springer
FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor
that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the …

FOXM1 and cancer: faulty cellular signaling derails homeostasis

D Kalathil, S John, AS Nair - Frontiers in oncology, 2021 - frontiersin.org
Forkhead box transcription factor, FOXM1 is implicated in several cellular processes such as
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …

Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes

E Ntoumou, M Tzetis, M Braoudaki, G Lambrou… - Clinical …, 2017 - Springer
Background MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In
this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients …

Hypoxia-induced TUFT1 promotes the growth and metastasis of hepatocellular carcinoma by activating the Ca2+/PI3K/AKT pathway

C Dou, Z Zhou, Q Xu, Z Liu, Y Zeng, Y Wang, Q Li… - Oncogene, 2019 - nature.com
Abstract Tuftelin1 (TUFT1), an acidic protein constituent of develo** and mineralizing
tooth tissues, is regulated by hypoxia and the Hedgehog signaling pathway. We investigated …

HNRNPA2/B1 is upregulated in endocrine-resistant LCC9 breast cancer cells and alters the miRNA transcriptome when overexpressed in MCF-7 cells

CM Klinge, KM Piell, CS Tooley, EC Rouchka - Scientific reports, 2019 - nature.com
MicroRNAs are dysregulated in breast cancer. Heterogeneous Nuclear Ribonucleoprotein
A2/B1 (HNRNPA2/B1) is a reader of the N (6)-methyladenosine (m6A) mark in primary …

RETRACTED: Circular RNA circ_0001946 acts as a competing endogenous RNA to inhibit glioblastoma progression by modulating miR‐671‐5p and CDR1

X Li, H Diao - Journal of cellular physiology, 2019 - Wiley Online Library
Objectives In many malignant tumors, circRNAs play an important role. However, the
biological role and clinical significance of circRNAs remain unclear. In this study, we …

Identification of plasma microRNA expression changes in multiple system atrophy and Parkinson's disease

H Uwatoko, Y Hama, IT Iwata, S Shirai, M Matsushima… - Molecular Brain, 2019 - Springer
MicroRNAs (miRNAs) are endogenous small (18–25 nt), single-stranded, non-coding RNAs
that play key roles in post-transcriptional gene expression regulation. The expression …

LncRNA UCA1-miR-507-FOXM1 axis is involved in cell proliferation, invasion and G0/G1 cell cycle arrest in melanoma

Y Wei, Q Sun, L Zhao, J Wu, X Chen, Y Wang, W Zang… - Medical Oncology, 2016 - Springer
Recently, the incidence of melanoma has been on the rise. Patients with distant metastasis
share poor prognosis. Increasing studies have been conducted to clarify the molecular …

MicroRNAs association with azoospermia, oligospermia, asthenozoospermia, and teratozoospermia: a systematic review

Y Daneshmandpour, Z Bahmanpour… - Journal of assisted …, 2020 - Springer
Infertility is a major health problem across the world. One of the main reasons for male
infertility are defects in sperm. Semen analysis is the most common test utilized to evaluate …