Therapeutic potential of palm oil vitamin E-derived tocotrienols in inflammation and chronic diseases: Evidence from preclinical and clinical studies

Z Zainal, H Khaza'ai, AK Radhakrishnan… - Food Research …, 2022 - Elsevier
Palm oil is rich in tocotrienols (T3s), a type of vitamin E that has garnered considerable
research interest as it exhibits anti-inflammatory as well as antioxidant characteristics that …

Unraveling the peculiar features of mitochondrial metabolism and dynamics in prostate cancer

F Fontana, M Anselmi, P Limonta - Cancers, 2023 - mdpi.com
Simple Summary Mitochondria are organelles involved in different biological processes,
including tumorigenesis. Accumulating evidence strongly supports that, despite the …

[HTML][HTML] Neuroprotective effect of rice bran enzymatic extract-supplemented diets in a murine model of Parkinsońs disease

E Gavilán, A Flores, A Castaño, L Martin-Presas… - Journal of Functional …, 2024 - Elsevier
Neurodegenerative disorders such as Parkinson's disease, present a global health concern
with limited therapeutic options. In this context, dietary interventions have emerged as a …

[HTML][HTML] Tocotrienols provide radioprotection to multiple organ systems through complementary mechanisms of antioxidant and signaling effects

SA Shrum, U Nukala, S Shrimali, EN Pineda, KJ Krager… - Antioxidants, 2023 - mdpi.com
Tocotrienols have powerful radioprotective properties in multiple organ systems and are
promising candidates for development as clinically effective radiation countermeasures. To …

Annatto (Bixa orellana) seeds, palm (Elaeis guineensis) oils, and St. John's wort (Hypericum perforatum) aerial parts as sources of rare prenyllipids

P Górnaś, I Mišina, D Lazdiņa - European Food Research and Technology, 2025 - Springer
Tocopherols (Ts) are common lipophilic antioxidants, the most prevalent being α-T and γ-T,
while tocotrienols (T3s) are considerably rarer. In recent years, tocotrienols have gained the …

The niacin rebirth: revisiting the potential of nicotinic acid therapy for cardiovascular disease and niacin supplementation for healthy aging

J Keenan - Medical Research Archives, 2024 - esmed.org
The aging of the global population and the associated increase in chronic disease burden
requires a paradigm shift in how we care for older adults, one that could benefit from …

[HTML][HTML] Exploring the anti-inflammatory activities, mechanism of action and prospective drug delivery systems of tocotrienol to target neurodegenerative diseases

AM Mathew, S Bhuvanendran, RS Nair… - …, 2023 - pmc.ncbi.nlm.nih.gov
A major cause of death in the elderly worldwide is attributed to neurodegenerative diseases,
such as AD (Alzheimer's disease), PD (Parkinson's disease), ALS (Amyotrophic lateral …

A Novel Supplement Regimen for Healthy Aging: A Case Series

J Keenan - Medical Research Archives, 2024 - esmed.org
Objective: This case series aims to evaluate a novel supplement regimen for healthy aging
in older adults, assess its potential to reduce reliance on prescription drugs like metformin …

[PDF][PDF] Health Benefits of Palm Oil

Y Noorzianna, A Manaf - 2022 - oer.ums.edu.my
In recent times there has been a growing research interest in palm oil, one of the major
edible plant oils in the tropical countries because of its various uses and nutritional value …