The Wnt/beta-catenin pathway is a family of proteins that is implicated in many vital cellular
functions such as stem cell regeneration and organogenesis. Several intra-cellular signal …

The mammalian stress-activated families of mitogen-activated protein kinases (MAPKs)
were first elucidated in 1994, and by 2001, substantial progress had been made in …

The Wnt signaling pathway is an ancient and evolutionarily conserved pathway that
regulates crucial aspects of cell fate determination, cell migration, cell polarity, neural …

The liver has a multitude of functions which are necessary to maintain whole body
homeostasis. This requires that various metabolic pathways can run in parallel in the most …

During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

Wnt signaling is one of the central mechanisms regulating tissue morphogenesis during
embryogenesis and repair. The pivot of this signaling cascade is the Wnt ligand, which binds …

The development of bone‐rebuilding anabolic agents for potential use in the treatment of
bone loss conditions, such as osteoporosis, has been a long‐standing goal. Genetic studies …

Resistance to therapy is the major hurdle in the current cancer management. Cancer cells
often rewire their cellular process to alternate mechanisms to resist the deleterious effect …

The roles of the Wnt signalling pathway in several developmental processes, including
synaptic differentiation, are well characterized. The expression of Wnt ligands and Wnt …

Amyloid oligomers have emerged as the most toxic species of amyloid-β (Aβ). This
hypothesis might explain the lack of correlation between amyloid plaques and memory …